3020070
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  Soluble Transferrin Receptor, Serum or Plasma

STFR

Ordering Recommendation

New York DOH Approval Status

This test is New York state approved.

Specimen Required

Patient Preparation
Collect

Serum separator tube or plasma separator tube. Also acceptable: green (lithium heparin).

Specimen Preparation

Transfer 1 mL serum or plasma to an ARUP standard transport tube. (Min: 0.4 mL)

Storage/Transport Temperature

Refrigerated.

Unacceptable Conditions

Contaminated, severely hemolyzed, icteric, or lipemic specimens.

Remarks
Stability

After separation from cells: Ambient: 5 days; Refrigerated: 1 week; Frozen: 1 month (avoid repeated freeze/thaw cycles)

Methodology

Quantitative Chemiluminescent Immunoassay (CLIA)

Performed

Sun-Sat

Reported

Within 24 hours

Reference Interval

Test Number
 Components
 Reference Interval
  Soluble Transferrin Receptor Male - 18 years & older: 2.2-5.0 mg/L
Female - 18 years & older: 1.9-4.4 mg/L

Interpretive Data

The Beckman Coulter Access sTfR immunoassay is intended as an aid in the diagnosis of iron deficiency anemia, especially in patients with chronic disease. In adult patients with anemia, an sTfR result greater than or equal to 1.55 mg/L is 86 percent sensitive and 49 percent specific for the presence of iron deficiency anemia, alone or in combination with anemia of chronic disease. The sTfR assay is not intended to be used in isolation; results should be interpreted in conjunction with the patient’s clinical presentation and other diagnostic tests, such as other indicators of iron status (refer to table below).


Test for Changes in: Iron Deficiency Anemia Anemia of Chronic Disease Iron Deficiency & Anemia of Chronic Disease
Ferritin Iron Sores Low High Normal or High
TIBC Iron Status High Low Normal or High
Serum Iron Iron Status Low Low Low
sTfR Iron Status High Normal High

Compliance Category

FDA

Note

Hotline History

View Hotline History

 

Hotline History

Date of Change
Test Name Change
Methodology
Performance/Reported Schedule
Specimen Requirements
Reference Interval
Interpretive Data
Note
CPT Code
Component Change
Other Interface Change
New Test
Inactive
10/20/2025
X
N/A

CPT Codes

84238

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Components

Component Test Code* Component Chart Name LOINC
0070283 Soluble Transferrin Receptor 30248-9
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.

Aliases

  • sTfR
  • TfR
  • Transferrin Receptor
  • Transferrin Receptor Level
Soluble Transferrin Receptor, Serum or Plasma