3019951
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Genome Sequencing, Familial Comparator

WGS FM

Ordering Recommendation

Use to submit parental or other familial comparator samples associated with a proband sample for Genome Sequencing (3019943). If reporting of secondary findings, including pathogenic variants in the American College of Medical Genetics and Genomics (ACMG) recommended genes, is desired for comparator samples, indicate opt-in status on the proband’s Genome Sequencing Intake Form.

New York DOH Approval Status

This test is not New York state approved. ARUP cannot facilitate testing for New York state clients. Please work directly with a New York state-approved laboratory.

Specimen Required

Patient Preparation
Collect

Preferred: Whole blood in lavender (EDTA) or pink (EDTA) Acceptable: Oragene(TM) saliva collection kit, or equivalent saliva collection device, collected in accordance with manufacturer instructions. Saliva in collection device suitable for human DNA extraction.
New York State Clients: ARUP cannot facilitate testing for New York patients. Please work directly with a New York-approved laboratory.

Specimen Preparation

Transport 2 mL whole blood (Min: 0.5 mL) or 2 mL saliva.

Storage/Transport Temperature

Refrigerated.

Unacceptable Conditions
Remarks

Refer to Genome Sequencing (ARUP test code 3019943) for proband specimen requirements.
This test is used for parental or other familial comparator samples associated with a proband sample submitted for Genome Sequencing (ARUP test code 3019943). Comparator samples must be submitted within 7 days of the proband’s sample. Please list the name/DOB of submitted familial comparators on the proband’s Genome Sequencing Intake Form.
If reporting of secondary findings is desired for comparator individual(s), indicate opt-in status on the proband’s Genome Sequencing Intake Form (additional charges apply).

Stability

Ambient: 72 hours; Refrigerated: 1 week; Frozen: Unacceptable

Methodology

Qualitative Massively Parallel Sequencing

Performed

Varies

Reported

14-21 days

Reference Interval

Interpretive Data

Refer to report.

Compliance Category

Note

Parental or other familial comparator samples are used to aid interpretation of the proband's genome sequencing data.
Contact ARUP's genetic counselors at 800-242-2787 ext. 2141 with questions about test submission.

Hotline History

N/A

CPT Codes

NA

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Components

Component Test Code* Component Chart Name LOINC
3019952 WGS FM Interp 86206-0
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.

Aliases

  • ACMG Incidental Findings
  • ACMG Secondary Findings
  • Familial Genome Control
  • Parental Genome Control
  • WGS Parental Comparator
  • WGS Control
  • Whole Genome Sequencing Familial Control
Genome Sequencing, Familial Comparator