Ordering Recommendation

Use to process and hold DNA for future pretransplant donor chimerism studies if there will be an extended delay between pretransplant sample collection and donor/posttransplant sample collection.

New York DOH Approval Status

This test is not New York state approved.

Specimen Required

Patient Preparation
Collect

  Whole blood or bone marrow in lavender (EDTA), pink (K2EDTA), or yellow (ACD solution A or B). OR buccal brushes from recipient.

Specimen Preparation

  Transport 2 mL whole blood (Min: 1 mL), OR 1 mL bone marrow (Min: 1 mL) refrigerated, OR 2 buccal brushes (cytology brushes) in a sterile, dry tube ambient. (Min: 2 brushes)

Storage/Transport Temperature

  Whole blood: Refrigerated. Buccal brush: Ambient.

Unacceptable Conditions

  Plasma, serum

Remarks

  Posttransplant results will be compared to pretransplant recipient and donor genotypes; therefore, donor and recipient specimens must be obtained and genotyped before the transplant event occurs.

Stability

  Whole Blood: Room temperature: 1 week; Refrigerated: 1 month; Frozen: Unacceptable
Buccal Brush: Room temperature: 1 week

Methodology

  Quantitative Polymerase Chain Reaction (PCR)

Performed

    Sun-Sat

Reported

    Varies

Reference Interval

Interpretive Data



Compliance Category

Modified FDA

Note

  Extract and hold.

Hotline History

N/A

CPT Codes

  NA

Components

Component Test Code* Component Chart Name LOINC
3005463 Chimerism Donor, Specimen
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.

Aliases

Chimerism, Donor, Pretransplant Process and Hold