3019585
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Antimicrobial Susceptibility - Carbapenemase Detection by CARBA5

MA CARBA5

Ordering Recommendation

Detects the presence of predominant carbapenemases (KPC, NDM, VIM, OXA-48, IMP) responsible for resistance to carbapenems and other beta-lactam antibiotics.

New York DOH Approval Status

This test is New York state approved.

Specimen Required

Patient Preparation
Collect

Actively growing Enterobacterales or Pseudomonas aeruginosa in pure culture.

Specimen Preparation

Transport sealed container with pure culture on agar slant/bacterial transport media. Place each specimen in an individually sealed bag.

Storage/Transport Temperature
Unacceptable Conditions

Specimen: FFPE and specimens in formalin. Rectal eSwab.

Remarks

Isolate identification (for cultures) and specimen source required.

Stability

Ambient: 1 week; Refrigerated: 1 week; Frozen: Unacceptable

Methodology

Qualitative Immunochromatography

Performed

Sun-Sat

Reported

2-3 days

Reference Interval

Positive
Negative
See Note

Interpretive Data

NG-Test CARBA 5 is an in vitro rapid and visual multiplex immunochromatographic assay that detects one or more of five common types of carbapenemase enzymes (KPC (K), OXA-48-like (O), IMP (I), VIM (V), NDM (N)) in bacterial colonies. Liquid extraction buffer is used as a cell lysing solution when mixed with colonies. Monoclonal antibodies that individually recognize each of the five carbapenemases are immobilized on a nitrocellulose membrane.

Compliance Category

FDA

Note

An additional processing fee will be billed for all isolates not submitted in pure culture, as indicated in the specimen requirements.

If species identification is not provided, identification will be performed at ARUP. Additional charges apply.

Hotline History

View Hotline History

 

Hotline History

Date of Change
Test Name Change
Methodology
Performance/Reported Schedule
Specimen Requirements
Reference Interval
Interpretive Data
Note
CPT Code
Component Change
Other Interface Change
New Test
Inactive
06/02/2025
X
N/A

CPT Codes

87185 x5

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Components

Component Test Code* Component Chart Name LOINC
3019848 Carbapenemase Detection by CARBA 5 101672-4
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.

Aliases

  • Klebsiella pneumoniae carbapenemase
  • OXA-48
  • resistance mechanism
  • multi-drug resistance
  • NDM
  • NewDelhi metallo-B-lactamase
  • carbapenem-resistance
  • carbapenemase
  • KPC
  • CRE
  • Enterobacteriales
  • IMP
  • VIM
  • MA KPCPCR
  • MDR
Antimicrobial Susceptibility - Carbapenemase Detection by CARBA5