Connect Sign In
3017866
Dihydropyrimidine Dehydrogenase (DPYD) and UPD Glucuronosyltransferase 1A1 (UGT1A1) Genotyping
DPYDUGT1A1
Ordering Recommendation
Predicts risk of dose-related toxicity to 5-FU therapy. May be useful in dosage planning for individuals who will receive high-dose irinotecan, have personal or family history of sensitivity to irinotecan, or have experienced neutropenia while receiving irinotecan.
New York DOH Approval Status
This test is New York state approved.
Specimen Required
Patient Preparation
Collect
Two tubes of lavender (EDTA), pink (K2EDTA).
Specimen Preparation
Transport 3 mL whole blood in each tube. (Min: 1 mL in each tube)
Storage/Transport Temperature
Refrigerated.
Unacceptable Conditions
Heparinized specimens. Frozen specimens in glass collection tubes.
Remarks
Stability
Ambient: 72 hours; Refrigerated: 1 week
Methodology
Polymerase Chain Reaction (PCR)/Fluorescence Monitoring/Fragment Analysis
Performed
Varies
Reported
5-10 days
Reference Interval
Interpretive Data
Refer to report.
Compliance Category
Laboratory Developed Test (LDT)
Note
Hotline History
Hotline History
Date of Change
Test Name Change
Methodology
Performance/Reported Schedule
Specimen Requirements
Reference Interval
Interpretive Data
Note
CPT Code
Component Change
Other Interface Change
New Test
Inactive
N/A
CPT Codes
81232; 81350
Components
| Component Test Code* | Component Chart Name | LOINC |
|---|---|---|
| 2013096 | DPYD Genotype | 45284-7 |
| 2013097 | DPYD Phenotype | 79719-1 |
| 3017865 | DPYD Interpretation | 79719-1 |
| 3017867 | UGT1A1 Genotyping Specimen | 66746-9 |
| 3017868 | UGT1A1 Genotyping Allele 1 | 51951-2 |
| 3017869 | UGT1A1 Genotyping Allele 2 | 51952-0 |
| 3017870 | UGT1A1 Genotyping Interpretation | 34509-0 |
| 3017872 | EER DPYD UGT1A1 | 11526-1 |
| 3018244 | DPYD Genotyping Specimen | 31208-2 |
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
- 5FU drug toxicity
- Capecitabine
- Dihydropyrimidine
- DPD
- DPYD
- DPYD genotyping
- Fegafur
- Irinotecan Toxicity
- Uftoral
- UGT1A1
- Xeloda
Dihydropyrimidine Dehydrogenase (DPYD) and UPD Glucuronosyltransferase 1A1 (UGT1A1) Genotyping
