Ordering Recommendation

Use to detect Treponema pallidum, Herpes simplex virus 1, and Herpes simplex virus 2 in genital and anorectal lesions/ulcers. 

New York DOH Approval Status

This test is New York state approved.

Specimen Required

Patient Preparation

Genital, anal, or rectal swabs with APTIMA Unisex Swab Specimen Collection kit (ARUP supply #28907) OR in Viral Transport Media (ARUP supply #12884) available online through eSupply using ARUP Connect, or contact ARUP Client Services at 800-522-2787.

Specimen Preparation

APTIMA Swab: Place blue swab in swab specimen transport tube, break shaft off at score line, then recap tube.
Swab in Viral Transport Media (VTM): Transfer swab to viral transport media.

Storage/Transport Temperature


Unacceptable Conditions

Serum, plasma


Specimen source required


Ambient: 3 days; Refrigerated: 1 month; Frozen: 1 month


Qualitative Polymerase Chain Reaction (PCR)


Tue, Thu, Sat


1-5 days

Reference Interval

Interpretive Data

A negative result does not rule out the presence of PCR inhibitors in the patient specimen or test-specific nucleic acid in concentrations below the level of detection by this assay.

Compliance Category

Laboratory Developed Test (LDT)


This test detects and differentiates Treponema pallidum, Herpes simplex virus 1, and Herpes simplex virus 2.

Hotline History


CPT Codes

87529 x2, 87798


Component Test Code* Component Chart Name LOINC
3017666 GUDPPCR TH, Source
3017667 HSV type 1, PCR 91859-9
3017669 HSV type 2, PCR 91858-1
3017671 T. pallidum, PCR 91846-6
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.


  • Genital ulcer
  • Herpes simplex virus 1
  • Herpes simplex virus 2
  • Syphilis
  • Treponema pallidum
Treponema pallidum, HSV-1 and HSV-2 by PCR