Ordering Recommendation

This quantitative test is appropriate for therapeutic monitoring of BCR-ABL1 minor (p190) positive chronic myeloid leukemia (CML) or acute lymphoblastic leukemia/lymphoma (ALL).

For patients with uncertain diagnoses or unknown forms of BCR-ABL1 fusion transcripts, consider ordering Diagnostic Qualitative BCR-ABL1 Assay with Reflex to p190 or p210 Quantitative Assays (3005839).

New York DOH Approval Status

This test is New York state approved.

Specimen Required

Patient Preparation

Whole blood or bone marrow in lavender (EDTA).

Specimen Preparation

Whole Blood: Transport 5 mL whole blood. (Min: 3 mL)
Bone Marrow: Transport 3 mL bone marrow. (Min: 1 mL)
Refrigerate immediately. Specimens must be received within 48 hours of collection due to lability of RNA.

Storage/Transport Temperature

Whole Blood or Bone Marrow: CRITICAL REFRIGERATED. Separate specimens must be submitted when multiple tests are ordered.

Unacceptable Conditions

Serum, plasma, extracted DNA, CSF, FFPE tissue, ambient whole blood, or frozen whole blood or bone marrow.
Specimens collected in anticoagulants other than EDTA. Severely hemolyzed or clotted specimens.
Ambient bone marrow specimens past 7 days will be canceled.
Refrigerated whole blood or bone marrow specimens past 7 days will be canceled.


Ambient: Unacceptable; Refrigerated: 48 hours; Frozen: Unacceptable


Quantitative Reverse Transcription Polymerase Chain Reaction




5-9 days

Reference Interval

Interpretive Data

Refer to report.

Compliance Category

Laboratory Developed Test (LDT)


For p210 fusion form (major breakpoint), order BCR-ABL1, Major (p210), Quantitative (ARUP test code 3005840).

Hotline History


CPT Codes



Component Test Code* Component Chart Name LOINC
3016971 Quant BCR-ABL1, Minor (p190), Source 31208-2
3016972 Quant BCR-ABL1, Minor (p190), Result 21823-0
3016973 Quant BCR-ABL1, Minor (p190), Ratio 52132-8
3016975 Quant BCR-ABL1, Minor (p190), EER 11526-1
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.


  • Minor
  • p190
  • Ph+
  • philadelphia chromosome
  • t(9;22)
Quantitative Detection of BCR-ABL1, Minor Form (p190)