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Recommendations when to order or not order the test. May include related or preferred tests.
May aid in the diagnosis of bilateral rapidly progressive vision loss and suspected cancer-associated retinopathy. This test only evaluates for the presence of autoantibodies to recoverin. If a panel test is clinically indicated, consider ordering Autoimmune Vision Loss Panel, Serum (3016804) to assess for the presence of antibodies to recoverin and CV2/CRMP5.
New York DOH Approval Status
Indicates test has been approved by the New York State Department of Health.
This test is New York state approved.
Specimen Required
Patient PreparationInstructions patient must follow before/during specimen collection.
CollectSpecimen type to collect. May include collection media, tubes, kits, etc.
Serum separator tube.
Specimen PreparationInstructions for specimen prep before/after collection and prior to transport.
Separate serum from cells ASAP or within 2 hours of collection. Transfer 1 mL serum to an ARUP standard transport tube. (Min: 0.30 mL)
Storage/Transport TemperaturePreferred temperatures for storage prior to and during shipping to ARUP. See Stability for additional info.
Refrigerated.
Unacceptable ConditionsCommon conditions under which a specimen will be rejected.
Plasma. Contaminated, heat-inactivated, hemolyzed, or lipemic specimens.
RemarksAdditional specimen collection, transport, or test submission information.
StabilityAcceptable times/temperatures for specimens. Times include storage and transport time to ARUP.
After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 month
Methodology
Process(es) used to perform the test.
Qualitative Immunoblot
Performed
Days of the week the test is performed.
Mon, Thu, Sat
Reported
Expected turnaround time for a result, beginning when ARUP has received the specimen.
1-4 days
Reference Interval
Normal range/expected value(s) for a specific disease state. May also include abnormal ranges.
Test Number
Components
Reference Interval
Recoverin Ab, IgG by Immunoblot, Serum
Negative
Interpretive Data
May include disease information, patient result explanation, recommendations, or details of testing.
Antibodies to recoverin are found in a subset of patients with cancer-associated retinopathy. Symptoms of rapidly progressive bilateral vision loss may precede detection of cancer, and a positive test result should prompt a search for malignancy, most often small cell lung adenocarcinoma. A negative test result does not rule out the diagnosis of autoimmune vision loss. Results should be interpreted in the context of the patient's clinical history, neurologic and ophthalmologic exam, and other laboratory findings.
The American Medical Association Current Procedural Terminology (CPT) codes published in ARUP's Laboratory Test Directory are provided for informational purposes only. The codes reflect our interpretation of CPT coding requirements based upon AMA guidelines published annually. CPT codes are provided only as guidance to assist clients with billing. ARUP strongly recommends that clients confirm CPT codes with their Medicare administrative contractor, as requirements may differ. CPT coding is the sole responsibility of the billing party. ARUP Laboratories assumes no responsibility for billing errors due to reliance on the CPT codes published.
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
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