3016679
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RhC/c (RHCE) Antigen Genotyping, Fetal

RHCGENO FE
Example Reports
Cultured CC
Direct cc

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Additional Technical Information

Ordering Recommendation

Fetal RhC/c genotyping to assess risk for alloimmune hemolytic disease. For parental or neonatal testing, refer to RhC/c (RHCE) Antigen Genotyping (3002002).

New York DOH Approval Status

This test is New York state approved.

Specimen Required

Patient Preparation
Collect

Amniotic fluid OR cultured amniocytes OR cultured CVS: Two T-25 flasks at 80 percent confluency.
AND Maternal whole blood: lavender (K2 or K3EDTA), pink (K2EDTA), or yellow (ACD solution A or B).
If the client is unable to culture, order test Cytogenetics Grow and Send (ARUP test code 0040182) in addition to this test and ARUP will culture upon receipt (culturing fees will apply).  If you have any questions, contact ARUP's Genetics Processing at 800-522-2787 ext. 3301.

Specimen Preparation

Amniotic fluid: Transport 10 mL amniotic fluid in a sterile container (min: 5 mL).
OR cultured amniocytes OR cultured CVS: Fill flasks with culture media. Backup cultures must be retained at the client's institution until testing is complete.
AND maternal whole blood: Transport 2 mL whole blood (min: 1 mL).

Storage/Transport Temperature

Amniotic fluid, cultured amniocytes or cultured CVS: CRITICAL ROOM TEMPERATURE. Must be received within 48 hours of shipment due to lability of cells.
Maternal whole blood: room temperature.

Unacceptable Conditions

Frozen specimens in glass collection tubes.

Remarks

Patient History Form is available on the ARUP website or by contacting ARUP Client Services.

Stability

Fetal specimens: Ambient: 48 hours; Refrigerated: 48 hours; Frozen: Unacceptable
Maternal whole blood: Ambient: 72 hours; Refrigerated: 1 week; Frozen: Unacceptable

Methodology

Polymerase Chain Reaction (PCR)/Fluorescence Monitoring/Fragment Analysis

Performed

Varies

Reported

3-10 days
If culture is required, an additional 1 to 2 weeks is required for processing time.

Reference Interval

By report

Interpretive Data

Refer to report.

Counseling and informed consent are recommended for genetic testing. Consent forms are available online.

Compliance Category

Modified FDA

Note

Hotline History

View Hotline History

 

Hotline History

Date of Change
Test Name Change
Methodology
Performance/Reported Schedule
Specimen Requirements
Reference Interval
Interpretive Data
Note
CPT Code
Component Change
Other Interface Change
New Test
Inactive
01/21/2025
X
08/21/2023
X
N/A

CPT Codes

0001U; 81265 Fetal Cell Contamination (FCC)

Are you an ARUP Client? Click here for your pricing.

Components

Component Test Code* Component Chart Name LOINC
0050548 Maternal Contamination Study Fetal Spec 59266-7
0050612 Maternal Contam Study, Maternal Spec 66746-9
3016680 RHC GENO, Fetal Specimen 31208-2
3016681 RhCc Genotype Fetal, Interpretation 46731-6
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.

Aliases

  • RHCE genotyping
RhC/c (RHCE) Antigen Genotyping, Fetal