Ordering Recommendation

Useful to assess current or past hepatitis B virus (HBV) infection. Panel includes HBV surface antigen, HBV surface antibody (quantitative), and HBV core IgG/IgM antibody.

New York DOH Approval Status

This test is New York state approved.

Specimen Required

Patient Preparation

Serum separator tube (SST).

Specimen Preparation

Separate serum from cells ASAP or within 2 hours of collection. Transfer 3.00 mL serum to an ARUP standard transport tube. (Min: 1.750 mL)

Storage/Transport Temperature


Unacceptable Conditions

Heparinized plasma. Specimens containing particulate material or obvious microbial contamination. Heat-inactivated, or severely hemolyzed.


After separation from cells: Ambient: 12 hours; Refrigerated: 7 days; Frozen: 30 days (avoid repeated freeze/thaw cycles).


Quantitative Chemiluminescent Immunoassay (CLIA)/Qualitative Chemiluminescent Immunoassay (CLIA)




1-2 days
If the HBsAg reflexes to the HBSAG CONF add 1-3 days.

Reference Interval

Test Number
Reference Interval
  Hepatitis B Surface Antibody
Less than 10.00 IU/L Negative
Greater than or equal to 10.00 IU/L Positive

  Hepatitis B Core Antibodies, Total Negative

Interpretive Data

Compliance Category



The HBV core total assay tests for IgG and IgM antibodies, but does not differentiate between them.

HBsAb results greater than 1,000.00 IU/L are reported as greater than 1,000.00 IU/L

If results for HBsAg screen are repeatedly reactive with an index value between 1.00 and 50.00, then HBsAg Confirmation will be added. Additional charges apply.

Hotline History


CPT Codes

86706; 86704; 87340; if reflexed, add 87341


Component Test Code* Component Chart Name LOINC
0020089 Hepatitis B Surface Antigen 5196-1
0020090 Hepatitis B Surface Antibody 5193-8
0020091 Hepatitis B Core Antibodies, Total 13952-7
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.


  • Anti Core Antibodies
  • Anti-HBs Titer, S
  • Anti-Hepatitis Bc
  • Anti-Hepatitis Bs
  • Antibody Titer to Hep B Surface Ag
  • Antibody to Hepatitis B Surface Antigen
  • Antibody to Hepatitis Bc
  • Core Antibody IgG/IgM
  • HBsAB
  • HBsAg
  • HBsAg screen
  • HBV Core Total
  • HBV Hep B Surface Ab
  • HBV Surface Antigen
  • Hep B Core Ab IgG/IgM, Hep Bc Ab IgG/IgM
  • Hep B Core Total Ab
  • Hep B Surface Antigen
  • Hepatitis B
  • Hepatitis B Immune Status Profile, Serum
  • Hepatitis B Immunity
  • Hepatitis B Surface Antibody, Quantitative
  • Hepatitis Bs
  • Hepatitis Bs Ag
HBV Exposure Panel