Ordering Recommendation

Serum antibody panel for suspected common tickborne diseases: Lyme disease, anaplasmosis, ehrlichiosis, and babesiosis.

New York DOH Approval Status

This test is New York state approved.

Specimen Required

Patient Preparation

Serum separator tube (SST) or plain red.

Specimen Preparation

Separate serum from cells ASAP or within 2 hours of collection. Transfer 3 mL serum to an ARUP standard transport tube. (Min: 1.6 mL)

Storage/Transport Temperature

Preferred transport temp: Refrigerated. Also acceptable: Frozen

Unacceptable Conditions

CSF or plasma. Contaminated, heat-inactivated, hemolyzed, icteric, or severely lipemic specimens.


After separation from cells: Ambient: 48 hours; Refrigerated: 10 days; Frozen: 1 month (avoid repeated freeze/thaw cycles)


Semi-Quantitative Indirect Fluorescent Antibody (IFA)/Semi-Quantitative Enzyme-Linked Immunosorbent Assay (ELISA)/Qualitative Immunoblot




1-5 days

Reference Interval

Test Number
Reference Interval
  Ehrlichia chaffeensis Antibody, IgG Less than 1:64
  A. Phagocytophilum Antibody, IgG Less than 1:80
  Babesia microti IgG Less than 1:16
  B. burgdorferi VlsE1/pepC10 Abs, ELISA 0.90 IV or less

Interpretive Data

Refer to report.

Compliance Category

Laboratory Developed Test (LDT)


If VlsE1/pepC10 antibodies by ELISA is 0.91 IV or greater, then IgG and IgM by Immunoblot will be added. Additional charges apply.

Hotline History


CPT Codes

86753; 86666 x2; 86618; if reflexed, add 86617 x2


Component Test Code* Component Chart Name LOINC
0051004 Ehrlichia chaffeensis Antibody, IgG 47405-6
0093049 Babesia microti IgG 16117-4
0097317 A. Phagocytophilum Antibody, IgG 23877-4
3003258 B. burgdorferi VlsE1/pepC10 Abs, ELISA 100711-1
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.


  • Anaplasma phagocytophilum
  • Babesia microti
  • Borrelia burgdorferi
  • Ehrlichia chaffeensis
  • HME (Human Monocytotropic Ehrlichiosis)
  • Human Granulocytic Anaplasmosis (HGA)
  • Lyme Disease
  • Tick-Borne Diseases
Tickborne Disease Antibodies Panel