NR4A3 Rearrangement by FISH
Ordering Recommendation
New York DOH Approval Status
Specimen Required
Tumor Tissue
Formalin fix (10 percent neutral buffered formalin) and paraffin embed tissue. Protect paraffin block from excessive heat. Transport tissue block or 5 unstained (4-micron thick sections) positively charged slides in a tissue transport kit (ARUP supply #47808) highly recommended, and available online through eSupply using ARUP Connect™ or contact ARUP Client Services at 800- 522-2787. (Min. 2 slides)
Room temperature. Also acceptable: Refrigerated. Ship in cooled container during summer months.
Specimens fixed or processed in alternative fixatives (alcohol, Prefer) or heavy metal fixatives (B-4 or B-5). No tumor in tissue. Decalcified specimens.
Include surgical pathology report.
If multiple specimens (blocks or slides) are sent to ARUP, they must be accompanied by one of the following: an order comment indicating that the ARUP pathologist should choose the specimen most appropriate for testing (e.g., "Choose best block"), or individual orders for each sample submitted. A Pathologist Block Selection Fee (ARUP test code 3002076) will be added to orders that utilize the first option. If multiple specimens are sent to ARUP without a request for pathologist block/slide selection or individual orders, they will be held until clarification is provided.
Ambient: Indefinitely; Refrigerated: Indefinitely; Frozen: Unacceptable
Methodology
Qualitative Fluorescence in situ Hybridization (FISH)
Performed
Mon-Sat
Reported
3-7 days
Reference Interval
Interpretive Data
Laboratory Developed Test (LDT)
Note
Hotline History
Hotline History
CPT Codes
88366
Components
Component Test Code* | Component Chart Name | LOINC |
---|---|---|
3000703 | Scoring Method | 81304-8 |
3006358 | NR4A3 FISH Result | 103558-3 |
3006360 | Total Cell Count | 78236-7 |
3006361 | NR4A3 FISH Reference Number | 94736-6 |
3006362 | NR4A3 FISH Source | 31208-2 |
Aliases
- extraskeletal myxoid chondrosarcoma
- NR4A3 FISH
- NR4A3 Gene Rearrangement