Ordering Recommendation

New York DOH Approval Status

This test is New York state approved.

Specimen Required

Patient Preparation
Collect

Tumor Tissue

Specimen Preparation

Formalin fix (10 percent neutral buffered formalin) and paraffin embed tissue. Protect paraffin block from excessive heat. Transport tissue block or 5 unstained (4-micron thick sections) positively charged slides in a tissue transport kit (ARUP supply #47808) highly recommended, and available online through eSupply using ARUP Connect™ or contact ARUP Client Services at 800- 522-2787. (Min. 2 slides)

Storage/Transport Temperature

Room temperature. Also acceptable: Refrigerated. Ship in cooled container during summer months.

Unacceptable Conditions

Specimens fixed or processed in alternative fixatives (alcohol, Prefer) or heavy metal fixatives (B-4 or B-5). No tumor in tissue. Decalcified specimens.

Remarks

Include surgical pathology report.
If multiple specimens (blocks or slides) are sent to ARUP, they must be accompanied by one of the following: an order comment indicating that the ARUP pathologist should choose the specimen most appropriate for testing (e.g., "Choose best block"), or individual orders for each sample submitted. A Pathologist Block Selection Fee (ARUP test code 3002076) will be added to orders that utilize the first option. If multiple specimens are sent to ARUP without a request for pathologist block/slide selection or individual orders, they will be held until clarification is provided.

Stability

Ambient: Indefinitely; Refrigerated: Indefinitely; Frozen: Unacceptable

Methodology

Qualitative Fluorescence in situ Hybridization (FISH)

Performed

Mon-Sat

Reported

3-7 days

Reference Interval

Interpretive Data



Compliance Category

Laboratory Developed Test (LDT)

Note

Hotline History

N/A

CPT Codes

88366

Components

Component Test Code* Component Chart Name LOINC
3000703 Scoring Method 81304-8
3006358 NR4A3 FISH Result 103558-3
3006360 Total Cell Count 78236-7
3006361 NR4A3 FISH Reference Number 94736-6
3006362 NR4A3 FISH Source 31208-2
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.

Aliases

  • extraskeletal myxoid chondrosarcoma
  • NR4A3 FISH
  • NR4A3 Gene Rearrangement
NR4A3 Rearrangement by FISH