Mycoplasmoides genitalium Detection and Macrolide Resistance by PCR
Use to detect Mycoplasmoides (Mycoplasma) genitalium and predict resistance to macrolide antibiotics.
Qualitative Polymerase Chain Reaction (PCR)
New York DOH Approval Status
Genital swab, rectal swab, or urine.
Transfer swab or 1 mL urine to viral transport media (ARUP supply #12884) available online through eSupply using ARUP Connect™ or contact ARUP Client Services at 800-522-2787.
Neat urine: Transfer 1mL of urine to sterile container. (Min: 0.5 mL)
Specimen source required
Ambient: 48 hours; Refrigerated: 10 days; Frozen: 14 days
Macrolide drug resistance is predicted based on melt probe analysis. Common resistance associated mutations occur at positions A2058, A2059, and A2062 (E. coli numbering) of the 23S rRNA gene. Other mutations of unknown significance may be detected by this assay, however this was not observed in samples sequenced during assay development and validation. This test is intended for use in conjunction with clinical presentation.
Laboratory Developed Test (LDT)
|Component Test Code*||Component Chart Name||LOINC|
|3006345||M. genitalium source|
|3006346||M. genitalium by PCR|
|3006347||Macrolide Resistance by PCR|
- Azithromycin drug resistance
- drug resistance
- M. genitalium
- Mycoplasma genitalium