Ordering Recommendation

Use to detect and quantify Epstein-Barr virus (EBV). For additional information regarding this test, please visit Epstein-Barr Virus by Quantitative NAAT, Plasma.

New York DOH Approval Status

This test is New York state approved.

Specimen Required

Patient Preparation
Collect

Lavender (EDTA), pink (K2EDTA), or plasma preparation tube (PPT).

Specimen Preparation

Separate from cells within 24 hours of collection. Transfer 2 mL plasma to an ARUP standard transport tube (ARUP supply #15824). Available online through eSupply using ARUP Connect™or contact ARUP Client Services at 800-522-2787. (Minimum volume, 1mL)

Storage/Transport Temperature

Frozen.

Unacceptable Conditions

Heparinized specimens, whole blood, serum, CSF, tissue, bone marrow, body fluid. Refer to Epstein-Barr Virus by Qualitative PCR (ARUP test code 0050246) for other sample types.

Remarks
Stability

After separation from cells: Ambient: 24 hrs; Refrigerated: 6 days; Frozen: 6 months

Methodology

Quantitative Polymerase Chain Reaction

Performed

Sun-Sat

Reported

1-4 days

Reference Interval

Not detected

Interpretive Data

The quantitative range of this test is 1.54-8.00 log IU/mL (35.0-100,000,000 IU/mL).

An interpretation of "Not Detected" does not rule out the presence of inhibitors or EBV DNA concentration below the level of detection of the assay. Care should be taken in the interpretation of any single viral load determination.

International standardization has improved comparability of assay results across laboratories, but discrepancies still exist due to commutability issues with the standard.

Compliance Category

FDA

Note

The limit of quantification for this assay is 1.54 log IU/mL (35.0 IU/mL). If the assay DETECTED the presence of the virus but was not able to accurately quantify the viral load, the test result will be reported as "Not Quantified, Detected."

Hotline History

N/A

CPT Codes

87799

Components

Component Test Code* Component Chart Name LOINC
3006080 EBV Qnt by NAAT, Plasma IU/mL 43730-1
3006081 EBV Qnt by NAAT, Plasma log IU/mL 100677-4
3006082 EBV Qnt by NAAT, Plasma Interp 5005-4
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.

Aliases

  • EBV quant
  • herpes
  • HHV-4
  • human herpesvirus 4
  • transplant
  • viral load monitoring
Epstein-Barr Virus by Quantitative NAAT, Plasma