Ordering Recommendation

Use to screen individuals with Merkel cell carcinoma for antibodies suggestive of current or prior infection with Merkel cell polyomavirus.

New York DOH Approval Status

This test is not New York state approved. There are no New York state-approved laboratories available. Submit a Non-Permitted Laboratory Request Form (NPL) to the NYDOH prior to collection of specimen. If NPL is approved by NYDOH, and sample is received at ARUP, testing will be performed.

Specimen Required

Patient Preparation

Plain red or serum separator tube (SST).

Specimen Preparation

Separate from cells ASAP or within 4 hours of collection. Transfer 2 mL serum to an ARUP Standard Transport Tube. (Min: 0.5 mL)
Test is not performed at ARUP; separate specimens must be submitted when multiple tests are ordered.

Storage/Transport Temperature

Frozen. Also acceptable: Refrigerated.

Unacceptable Conditions

Ambient: Unacceptable; Refrigerated: 1 week; Frozen: Indefinitely


Multiplex Bead Assay




21-31 days

Reference Interval

By report

Interpretive Data

Compliance Category

Performed by non-ARUP Laboratory


Screening for the Merkel cell polyomavirus VP1 capsid antibody is done once, on the first specimen submitted. Additional charges apply.

Hotline History


CPT Codes



Component Test Code* Component Chart Name LOINC
3005984 Merkel Oncoprotein Ab, Titer 18727-8
3005985 Merkel Oncoprotein Ab, Interpretation 11502-2
3005986 Prior Merkel Oncoprotein Ab 18727-8
3005987 Date of Prior Sample 51953-8
3005988 Merkel Disease Status, Interpretation 1 56850-1
3005989 Merkel Disease Status, Interpretation 2 56850-1
3005990 Merkel Ab SmT Method 62364-5
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.


  • MCC
  • MCPyV
  • polyomavirus oncoprotein antibodies
  • polyomavirus VP1 capsid antibody
  • small T antibodies
Merkel Cell Carcinoma Antibodies

Univ. of Washington/Laboratory Medicine