Recommended test to confirm a hereditary cause of gastric cancer in individuals with a personal or family history of disease. Testing minors for adult-onset conditions is not recommended; testing will not be performed in minors without prior approval. For additional information, please contact an ARUP genetic counselor at 800-242-2787 ext. 2141.
To compare this test to other hereditary cancer panels, refer to the ARUP Hereditary Cancer Panel Comparison table.
Massively Parallel Sequencing/Sequencing/Multiplex Ligation-dependent Probe Amplification
New York DOH Approval Status
Lavender or pink (EDTA) or yellow (ACD solution A or B).
Transport 3 mL whole blood. (Min: 2 mL)
Serum or plasma; grossly hemolyzed or frozen specimens; saliva, buccal brush, or swab; FFPE tissue; DNA.
Ambient: 72 hours; Refrigerated: 1 week; Frozen: Unacceptable
Refer to report.
Depends on Specimen/Source/Method
Genes Tested: APC*; BMPR1A*; CDH1*; CTNNA1*; EPCAM**; MLH1; MSH2; MSH6; PMS2; SMAD4; STK11; TP53
*One or more exons are not covered by sequencing and/or deletion/duplication analysis for the indicated gene; see Additional Technical Information.
**Deletion/duplication analysis of EPCAM (NM_002354) exon 9 only, sequencing is not available for this gene.
81201; 81203; 81292; 81294; 81295; 81297; 81298; 81300; 81317; 81319; 81403
|Component Test Code*||Component Chart Name||LOINC|
- Familial adenomatous polyposis
- Gastric adenocarcinoma and proximal polyposis of the stomach
- Hereditary diffuse gastric cancer
- Hereditary gastrointestinal cancer
- Hereditary stomach cancer
- Juvenile polyposis syndrome
- Li-Fraumeni syndrome
- Lynch syndrome
- Peutz-Jeghers syndrome