Ordering Recommendation

Use to submit required parental control samples for Rapid Whole Genome Sequencing (3005935) if reporting of secondary findings for parental samples is desired. Pathogenic variants in the American College of Medical Genetics recommended genes will be reported. If reporting of ACMG-recommended secondary findings for parental samples is not desired, refer to Rapid Whole Genome Sequencing, Familial Control (3005928).

Mnemonic

RWGS FRPT

Methodology

Massively Parallel Sequencing

Performed

Varies

Reported

5-7 days

New York DOH Approval Status

Specimens from New York clients will be sent out to a New York DOH approved laboratory, if possible.

Specimen Required

Patient Preparation
Collect

Lavender (EDTA) or yellow (ACD solution A or B). Peripheral blood required. Contact ARUP's genetic counselor at 800-242-2787 ext. 2141 prior to test submission

Specimen Preparation

Transport 2 mL whole blood. (Min: 0.5 mL)

Storage/Transport Temperature

Refrigerated.

Unacceptable Conditions
Remarks

This test is used for parental control samples associated with a proband sample submitted for RWGS NGS. A report will be provided for samples ordered using this test code. If a report for parental control sample is not desired, order RWGS FAM (3005928).

Stability

Ambient: 72 hours; Refrigerated: 1 week; Frozen: Unacceptable

Reference Interval

By report

Interpretive Data

Refer to report.

Compliance Category

Laboratory Developed Test (LDT)

Note

Parental samples are used to aid in interpretation of the proband's genome sequencing data. This test is ordered when a report of ACMG secondary findings is desired for submitted parental controls. For each parental specimen, please indicate on the intake form that the sample is control and reference the patient's name.

Hotline History

N/A

CPT Codes

NA

Components

Component Test Code* Component Chart Name LOINC
3005934 RWGS FRPT Int
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.

Aliases

  • ACMG incidental findings
  • ACMG secondary findings
Rapid Whole Genome Sequencing, Familial Control with Report