Hereditary Prostate Cancer Panel, Sequencing and Deletion/Duplication
Recommended test to confirm a hereditary cause of prostate cancer in individuals with a personal or family history. Testing minors for adult-onset conditions is not recommended; testing will not be performed in minors without prior approval. For additional information, please contact an ARUP genetic counselor at 800-242-2787 ext. 2141.
To compare this test to other hereditary cancer panels, refer to the Hereditary Cancer Panel Comparison table.
New York DOH Approval Status
Lavender or pink (EDTA) or yellow (ACD solution A or B).
New York State Clients: Lavender (K2EDTA or K3EDTA)
Transport 3 mL whole blood. (Min: 2 mL)
Serum or plasma; grossly hemolyzed or frozen specimens; saliva, buccal brush, or swab; FFPE tissue; DNA.
Ambient: 72 hours; Refrigerated: 1 week; Frozen: Unacceptable
New York State Clients: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: Unacceptable
Massively Parallel Sequencing/Sequencing/Multiplex Ligation-Dependent Probe Amplification (MLPA)
Refer to report.
Laboratory Developed Test (LDT)
Genes Tested: ATM; BRCA1*; BRCA2; CHEK2*; EPCAM**; HOXB13; MLH1; MSH2; MSH6; NBN; PALB2; PMS2; RAD51D; TP53
*One or more exons are not covered by sequencing and/or deletion/duplication analysis for the indicated gene; see Additional Technical Information.
**Deletion/duplication analysis of EPCAM (NM 002354) exon 9 only, sequencing is not available for this gene.
81408; 81162; 81403; 81292; 81294; 81295; 81297; 81298; 81300; 81307; 81317; 81319; 81351; 81479
|Component Test Code*||Component Chart Name||LOINC|
- hereditary breast and ovarian cancer (HBOC) syndrome
- Hereditary nonpolyposis colorectal cancer (HNPCC)
- Li-Fraumeni syndrome (LFS)
- Lynch syndrome