Ordering Recommendation

May aid in the diagnosis of legionellosis caused by infection with L. pneumophila.

Mnemonic

LEGION AB

Methodology

Semi-Quantitative Enzyme-Linked Immunosorbent Assay

Performed

Mon-Fri

Reported

1-4 days

New York DOH Approval Status

This test is New York DOH approved.

Specimen Required

Patient Preparation
Collect

Serum separator tube (SST) or plain red.

Specimen Preparation

Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.3 mL)

Storage/Transport Temperature

Preferred transport temp: Refrigerated. Also acceptable: Frozen

Unacceptable Conditions

Contaminated, heat-inactivated, hemolyzed, icteric, or lipemic specimens.

Remarks
Stability

After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 month

Reference Interval

≤0.90 IV Negative: No significant amount of IgG/IgM/IgA antibodies to L. pneumophila detected.
0.91 to 1.09 IV Equivocal: Recommend repeat testing in 1-3 weeks with fresh sample.
≥1.10 IV Positive - IgG/IgM/IgA antibodies specific to L. pneumophila suggesting current or prior infection. A positive result cannot distinguish between previous or active infection, therefore this result alone cannot be used to establish a diagnosis.

Interpretive Data



Compliance Category

FDA

Note

Hotline History

N/A

CPT Codes

86713

Components

Component Test Code* Component Chart Name LOINC
3005201 L. pneumophila (Types 1-6), Antibodies 30046-7
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.

Aliases

  • Legionnaire's disease, legionellosis
Legionella pneumophila Antibodies (Types 1-6), IgG, IgM, and IgA by ELISA