Ordering Recommendation

May aid in the diagnosis of legionellosis caused by infection with L. pneumophila.

New York DOH Approval Status

This test is New York state approved.

Specimen Required

Patient Preparation
Collect

Serum separator tube (SST) or plain red.

Specimen Preparation

Transfer 1 mL serum to an ARUP standard transport tube. (Min: 0.3 mL)

Storage/Transport Temperature

Preferred transport temp: Refrigerated. Also acceptable: Frozen

Unacceptable Conditions

Contaminated, heat-inactivated, hemolyzed, icteric, or lipemic specimens.

Remarks
Stability

After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 month

Methodology

Semi-Quantitative Enzyme-Linked Immunosorbent Assay (ELISA)

Performed

Mon, Fri

Reported

1-6 days

Reference Interval

Test Number
Components
Reference Interval
  L. pneumophila (Types 1-6), Antibodies 0.90 IV or less

Interpretive Data




Component
Interpretation
L. pneumophila (Types 1-6), Antibodies ≤0.90 IV      Negative: No significant amount of IgG/IgM/IgA antibodies to L. pneumophila detected.
0.91 to 1.09 IV  Equivocal: Recommend repeat testing in 1-3 weeks with fresh sample.
≥1.10 IV      Positive: IgG/IgM/IgA antibodies specific to L. pneumophila suggesting current or prior infection. A positive result cannot distinguish between previous or active infection, therefore this result alone cannot be used to establish a diagnosis.

Compliance Category

FDA

Note

Hotline History

N/A

CPT Codes

86713

Components

Component Test Code* Component Chart Name LOINC
3005201 L. pneumophila (Types 1-6), Antibodies 30046-7
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.

Aliases

  • Legionnaire's disease, legionellosis
Legionella pneumophila Antibodies (Types 1-6), IgG, IgM, and IgA by ELISA