Drug Detection Panel, Meconium, Qualitative
Ordering Recommendation
Use to detect and document fetal drug exposure during approximately the last trimester of a full-term pregnancy. For panel testing that includes THC metabolite, refer to Drug Detection Panel and THC Metabolite, Meconium, Qualitative (3006373).
New York DOH Approval Status
Specimen Required
All meconium (blackish material) excreted until milk/formula-based stool (yellow-green) appears.
Transport all available meconium (2g is preferred) to routine urine collection cup or Security Kit for Meconium/Umbilical Drug Detection (ARUP supply #51548) available online through eSupply using ARUP Connect™ or by contacting ARUP Client Services at 800-522-2787.
Refrigerated temperature.
Unknown fluids, pharmaceutical preparation, and breast milk. Diapers, cotton swabs, baby wipes, tongue depressors, bottles.
Ambient: 1 week; Refrigerated: 3 weeks; Frozen: 1 year
Methodology
Qualitative Liquid Chromatography-Tandem Mass Spectrometry
Performed
Sun-Sat
Reported
1-3 days
N/A
Reference Interval
Drugs covered and range of cutoff concentrations. | |||
---|---|---|---|
Drugs/Drug Classes |
Cutoff Concentrations (ng/g) |
Drugs/Drug Classes |
Cutoff Concentrations (ng/g) |
Buprenorphine | 20 | Amphetamine | 20 |
Norbuprenorphine | 20 | Benzoylecgonine | 20 |
Naloxone | 20 | m-OH-Benzoylecgonine | 20 |
Codeine | 20 | Cocaethylene | 20 |
Dihydrocodeine | 20 | Cocaine | 20 |
Fentanyl | 10 | MDMA (Ecstasy) | 20 |
Hydrocodone | 20 | Methamphetamine | 20 |
Norhydrocodone | 20 | Phentermine | 20 |
Hydromorphone | 20 | Alprazolam | 5 |
Meperidine | 20 | Alpha-OH-Alprazolam | 5 |
Methadone | 10 | Butalbital | 50 |
Methadone metabolite | 10 | Clonazepam | 5 |
6-Acetylmorphine | 20 | 7-Aminoclonazepam | 5 |
Morphine | 20 | Diazepam | 5 |
Methylphenidate | 20 | Lorazepam | 20 |
Oxycodone | 20 | Midazolam | 20 |
Noroxycodone | 20 | Alpha-OH-Midazolam | 20 |
Oxymorphone | 20 | Nordiazepam | 20 |
Tapentadol | 20 | Oxazepam | 20 |
Tramadol | 20 | Phenobarbital | 200 |
N-desmethyltramadol | 20 | Temazepam | 20 |
O-desmethyltramadol | 20 | Zolpidem | 10 |
Gabapentin | 20 | Phencyclidine (PCP) | 10 |
Mitragynine (Kratom) | 25 |
Interpretive Data
Methodology: Qualitative Liquid Chromatography/Tandem Mass Spectrometry
Detection of drugs in meconium is intended to reflect maternal drug use during approximately the last trimester of a full-term pregnancy. The pattern and frequency of drug(s) used by the mother cannot be determined by this test. A negative result does not exclude the possibility that a mother used drugs during pregnancy. Detection of drugs in meconium depends on the extent of maternal drug use, as well as drug stability, unique characteristics of drug deposition in meconium, and the performance of the analytical method. Drugs administered during labor and delivery may be detected. Detection of drugs in meconium does not insinuate impairment and may not affect outcomes for the infant. Interpretive questions should be directed to the laboratory.
For medical purposes only; not valid for forensic use.
Laboratory Developed Test (LDT)
Note
When ordering both meconium tests, unless ARUP is otherwise notified, testing will be performed in the following order of priority:
Drug Detection Panel (0.125g)
Marijuana (0.125g)
Hotline History
Hotline History
CPT Codes
80346; 80348; 80353; 80361; 80356; 80365; 80373; 80354; 80362; 80355; 80359; 80325; 80360; 80345; 80372; 80358; 83992; 80323; 80368 (Alt code: G0482)
Components
Component Test Code* | Component Chart Name | LOINC |
---|---|---|
3004673 | 6-Acetylmorphine, MEC, Qual | 32099-4 |
3004674 | 7-Aminoclonazepam, MEC, Qual | 61031-1 |
3004675 | Alpha-OH-Alprazolam, MEC, Qual | 61037-8 |
3004676 | Alpha-OH-Midazolam, MEC, Qual | |
3004677 | Alprazolam, MEC, Qual | 61038-6 |
3004678 | Amphetamine, MEC, Qual | 8144-8 |
3004679 | Benzoylecgonine, MEC, Qual | 8187-7 |
3004680 | Buprenorphine, MEC, Qual | |
3004681 | Butalbital, MEC, Qual | 32057-2 |
3004682 | Clonazepam, MEC, Qual | 61039-4 |
3004683 | Cocaethylene, MEC, Qual | 57945-8 |
3004684 | Cocaine, MEC, Qual | 40527-4 |
3004685 | Codeine, MEC, Qual | 29278-9 |
3004686 | Diazepam, MEC, Qual | 61074-1 |
3004687 | Dihydrocodeine, MEC, Qual | |
3004688 | Methadone Metabolite, MEC, Qual | 91030-7 |
3004689 | Fentanyl, MEC, Qual | 61042-8 |
3004690 | Gabapentin, MEC, Qual | |
3004691 | Hydrocodone, MEC, Qual | 57981-3 |
3004692 | Hydromorphone, MEC, Qual | 57982-1 |
3004693 | Lorazepam, MEC, Qual | 61044-4 |
3004694 | MDMA- Ecstasy, MEC, Qual | 40481-4 |
3004695 | Meperidine, MEC, Qual | 75647-8 |
3004696 | Methadone, MEC, Qual | 43595-8 |
3004697 | Methamphetamine, MEC, Qual | 29286-2 |
3004698 | Methylphenidate, MEC, Qual | 61050-1 |
3004699 | Midazolam, MEC, Qual | |
3004700 | m-OH-Benzoylecgonine, MEC, Qual | 91029-9 |
3004701 | Morphine, MEC, Qual | 29287-0 |
3004702 | Naloxone, MEC, Qual | |
3004703 | N-desmethyltramadol, MEC, Qual | |
3004704 | Norbuprenorphine, MEC, Qual | 82375-7 |
3004705 | Nordiazepam, MEC, Qual | 61051-9 |
3004706 | Norhydrocodone, MEC, Qual | |
3004707 | Noroxycodone, MEC, Qual | |
3004708 | O-desmethyltramadol, MEC, Qual | |
3004709 | Oxazepam, MEC, Qual | 61055-0 |
3004710 | Oxycodone, MEC, Qual | 32101-8 |
3004711 | Oxymorphone, MEC, Qual | |
3004712 | Phencyclidine- PCP, MEC, Qual | 8232-1 |
3004713 | Phenobarbital, MEC, Qual | 32108-3 |
3004714 | Phentermine, MEC, Qual | |
3004715 | Tapentadol, MEC, Qual | |
3004724 | Temazepam, MEC, Qual | 61061-8 |
3004725 | Tramadol, MEC, Qual | 93719-3 |
3004726 | Zolpidem, MEC, Qual | |
3004739 | EER Drug Detection Pan, MEC | 11502-2 |
3004740 | Drug Detection Panel, MEC | 58738-6 |
3016645 | Mitragynine, MEC, Qual |