Ordering Recommendation

Recommended single screening test to identify IgA competence and assess tTG IgA concentrations in individuals with suspected celiac disease.

Mnemonic

CELIAC ABS

Methodology

Quantitative Immunoturbidimetry/Semi-Quantitative Enzyme-Linked Immunosorbent Assay

Performed

Sun-Sat

Reported

1-2 days

New York DOH Approval Status

This test is New York DOH approved.

Specimen Required

Patient Preparation
Collect

Serum separator tube.

Specimen Preparation

Separate serum from cells ASAP or within 2 hours of collection. Transfer 3 mL serum to an ARUP Standard Transport Tube. (Min: 1.5 mL)

Storage/Transport Temperature

Refrigerated.

Unacceptable Conditions

Plasma. Contaminated, hemolyzed, grossly icteric or grossly lipemic specimens.

Remarks
Stability

After separation from cells: Ambient: Unacceptable; Refrigerated: 14 days; Frozen: 6 months (avoid repeated freeze/thaw cycles)

Reference Interval

Test Number
Components
Reference Interval
0050340 Immunoglobulin A Effective February 16, 2021
0-2 years: 2-126 mg/dL
3-4 years: 14-212 mg/dL
5-9 years: 52-226 mg/dL
10-14 years: 42-345 mg/dL
15-18 years: 60-349 mg/dL
19 years and older: 68-408 mg/dL

0097709 Tissue Transglutaminase (tTG) Antibody, IgA
3 U/mL or less Negative
4-10 U/mL Weak Positive
11 U/mL or greater Positive

Interpretive Data

Refer to report.

Compliance Category

FDA

Note

This is not a reflex test. Test 2008114, Celiac Disease Reflexive Cascade is the preferred reflex screening test for Celiac Disease.

Hotline History

N/A

CPT Codes

82784; 86364

Components

Component Test Code* Component Chart Name LOINC
0050340 Immunoglobulin A 2458-8
0097709 Tissue Transglutaminase (tTG) Ab, IgA 46128-5
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.

Aliases

Celiac Antibodies, Tissue Transglutaminase (tTG), IgA and IgA, Total