Ordering Recommendation

Use to confirm a diagnosis of familial Mediterranean fever (FMF) in a symptomatic individual and to guide appropriate treatment options. May also be useful as a diagnostic or carrier test for individuals with a family history of FMF.

Mnemonic

FMF NGS

Methodology

Massively Parallel Sequencing

Performed

Varies

Reported

3 weeks

New York DOH Approval Status

Specimens from New York clients will be sent out to a New York DOH approved laboratory, if possible.

Specimen Required

Patient Preparation
Collect

Lavender (EDTA) or Yellow (ACD Solution A or B).

Specimen Preparation

Transport 3 mL whole blood. (Min: 2 mL)

Storage/Transport Temperature

Refrigerated.

Unacceptable Conditions

Serum or plasma; grossly hemolyzed or frozen specimens

Remarks
Stability

Ambient: 72 hours; Refrigerated: 1 week; Frozen: Unacceptable

Reference Interval

By report

Interpretive Data

Refer to report.

Compliance Category

Laboratory Developed Test (LDT)

Note

Genes tested: MEFV

Hotline History

N/A

CPT Codes

81404

Components

Component Test Code* Component Chart Name LOINC
3004435 FMF Specimen 66746-9
3004436 FMF Interp 35138-7
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.

Aliases

  • FMF
  • Periodic fever
  • Recurrent Polyserositis
Familial Mediterranean Fever (MEFV) Sequencing