Ordering Recommendation

Use to detect neuron specific enolase, which may be a tumor marker for evaluation of neuroendocrine tumors.

Mnemonic

NSE S

Methodology

Quantitative Immunoassay

Performed

Mon, Wed, Fri

Reported

1-4 days

New York DOH Approval Status

Specimens from New York clients will be sent out to a New York DOH approved laboratory, if possible.

Specimen Required

Patient Preparation
Collect

Serum Separator Tube (SST). Also acceptable: Plain Red.

Specimen Preparation

Allow specimen to clot completely at room temperature. Separate from cells ASAP or within 2 hours of collection. Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.5 mL)

Storage/Transport Temperature

Refrigerated.

Unacceptable Conditions

Plasma. Hemolyzed specimens.

Remarks
Stability

Ambient: Unacceptable; Refrigerated: 1 week; Frozen: 1 year (avoid repeated freeze/thaw cycles)

Reference Interval

Less than or equal to 12.7 ng/mL

Interpretive Data

This assay is performed using the BRAHMS NSE Kryptor Immunoassay. Results obtained with different assay methods or kits cannot be used interchangeably. Results cannot be interpreted as absolute evidence of the presence or absence of malignant disease.

Compliance Category

Laboratory Developed Test (LDT)

Note

Hotline History

N/A

CPT Codes

86316

Components

Component Test Code* Component Chart Name LOINC
3004313 Neuron Specific Enolase, Serum 57371-7
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.

Aliases

Neuron Specific Enolase, Serum