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3004310
CYP2B6
2B6GENO
Ordering Recommendation
Use to assess genetic risk of abnormal drug metabolism for CYP2B6 substrates. May aid in drug selection and dose planning for drugs metabolized by CYP2B6.
New York DOH Approval Status
This test is New York state approved.
Specimen Required
Patient Preparation
Collect
Lavender (EDTA), pink (K2EDTA), or yellow (ACD solution A or B).
Specimen Preparation
Transport 3 mL whole blood. (Min: 1 mL)
Storage/Transport Temperature
Refrigerated.
Unacceptable Conditions
Plasma or serum. Specimens collected in sodium heparin or lithium heparin. Frozen specimens in glass collection tubes.
Remarks
Stability
Ambient: 72 hours; Refrigerated: 1 week; Frozen: 1 month
Methodology
Polymerase Chain Reaction (PCR)/Fluorescence Monitoring
Performed
Varies
Reported
5-10 days
Reference Interval
By report
Interpretive Data
Refer to report.
Counseling and informed consent are recommended for genetic testing. Consent forms are available online.
Compliance Category
Laboratory Developed Test (LDT)
Note
Hotline History
Hotline History
Date of Change
Test Name Change
Methodology
Performance/Reported Schedule
Specimen Requirements
Reference Interval
Interpretive Data
Note
CPT Code
Component Change
Other Interface Change
New Test
Inactive
N/A
CPT Codes
81479
Components
| Component Test Code* | Component Chart Name | LOINC |
|---|---|---|
| 3004492 | 2B6 Specimen | 66746-9 |
| 3004493 | CYP2B6 Genotype | 72882-4 |
| 3004494 | CYP2B6 Phenotype | 79720-9 |
| 3004495 | 2B6 Interpretation | 77202-0 |
| 3016891 | EER CYP2B6 | 11526-1 |
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
- efavirenz
- bupropion
- methadone
- CYP2B6
- 2B6
- Cytochrome P450 2B6
- nevirapine
CYP2B6
