Ordering Recommendation

Use to screen for mast cell activation disorders.

New York DOH Approval Status

This test is New York state approved.

Specimen Required

Patient Preparation

Patients taking aspirin or nonsteroidal anti-inflammatory drugs (NSAIDs) may have decreased concentrations of prostaglandin F2 alpha. If possible, discontinue for 2 weeks or 72 hours, respectively, prior to specimen collection.



Specimen Preparation

Transfer 5 mL urine to ARUP standard transport tubes. (Min: 4 mL)
Test is not performed at ARUP; separate specimens must be submitted when multiple tests are ordered.

Storage/Transport Temperature

Refrigerated. Also acceptable: Frozen.

Unacceptable Conditions

Ambient: 8 hours; Refrigerated: 2 weeks; Frozen: 1 month


Quantitative Liquid Chromatography-Tandem Mass Spectrometry /Colorimetry




3-11 days

Reference Interval

By Report

Interpretive Data

Compliance Category

Performed by non-ARUP Laboratory


Elevated levels of 2,3-dinor-11beta-prostaglandin F2 alpha (2,3 BPG) in urine are not specific for systemic mast cell disease and may be found in patients with angioedema, diffuse urticaria, or myeloproliferative diseases in the absence of diffuse mast cell proliferation.

Hotline History


CPT Codes

84150; 82570


Component Test Code* Component Chart Name LOINC
3004161 2,3 Dinor-11Beta-Prostaglandin F2a, U 97658-9
3004162 Creatinine, Random Urine 2161-8
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.


  • 11 Beta-Prostaglandin F2 Alpha
  • 11BPG
  • 2, 3 11 Beta-Prostaglandin F2 Alpha
  • 23BPG
  • BPG2
  • Mastocytosis
  • Prostaglandin
2,3 Dinor-11Beta-Prostaglandin F2 Alpha, Random Urine

Mayo Clinic Laboratories