3004090
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Apixaban Level

APIX
Example Reports
Example

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Specimen Collection and Handling

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Additional Technical Information

Ordering Recommendation

Use to measure apixaban concentration.

New York DOH Approval Status

This test is New York state approved.

Specimen Required

Patient Preparation
Collect

Lt. blue (sodium citrate). Refer to Specimen Handling at aruplab.com for hemostasis/thrombosis specimen handling guidelines.

Specimen Preparation

Transport 2 mL platelet-poor plasma. (Min: 1 mL)

Storage/Transport Temperature

CRITICAL FROZEN. Separate specimens must be submitted when additional tests are ordered.

Unacceptable Conditions

Serum. EDTA, oxalate, heparin, or plasma separator tubes, hemolyzed specimens.

Remarks

This test cannot be used to quantitate anticoagulants other than apixaban (Eliquis). This includes but is not limited to unfractionated heparin, low molecular weight heparin, rivaroxaban (Xarelto), edoxaban (Savaysa), and fondaparinux (Arixtra).

Stability

After separation from cells: Ambient: 4 hours; Refrigerated: Unacceptable; Frozen: 1 month

Methodology

Chromogenic Assay

Performed

Tue

Reported

1-8 days

Reference Interval

Not established

Interpretive Data

When 5 mg apixaban was administered twice daily for treatment of DVT and PE, apixaban steady state levels were as follows:
Peak: 59-302 ng/mL
Trough: 22-177 ng/mL
The lower limit of detection for this assay is 23 ng/mL.
For additional information, please refer to www.arupconsult.com

Compliance Category

Laboratory Developed Test (LDT)

Note

Hotline History

View Hotline History

 

Hotline History

Date of Change
Test Name Change
Methodology
Performance/Reported Schedule
Specimen Requirements
Reference Interval
Interpretive Data
Note
CPT Code
Component Change
Other Interface Change
New Test
Inactive
10/20/2025
X
N/A

CPT Codes

80299

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Components

Component Test Code* Component Chart Name LOINC
3004091 Apixaban 74214-8
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.

Aliases

  • Direct oral anti coagulant
  • Direct oral anti-coagulant
  • Direct oral anticoagulant
  • doac
  • Eliquis
Apixaban Level