Use to measure apixaban concentration.
New York DOH Approval Status
Lt. blue (sodium citrate). Refer to Specimen Handling at aruplab.com for hemostasis/thrombosis specimen handling guidelines.
Transport 2 mL platelet-poor plasma. (Min: 1 mL)
CRITICAL FROZEN. Separate specimens must be submitted when additional tests are ordered.
Serum. EDTA, oxalate, heparin, or plasma separator tubes, hemolyzed specimens.
This test cannot be used to quantitate anticoagulants other than Apixaban. This includes but is not limited to Unfractionated Heparin, Low Molecular Weight Heparin, Rivaroxaban (Xarelto), Edoxaban (Savaysa), and Fondaparinux (Arixtra).
After separation from cells: Ambient: 4 hours; Refrigerated: Unacceptable; Frozen: 1 month
When 5 mg apixaban was administered twice daily for treatment of DVT and PE, apixaban steady state levels were as follows:
Peak: 59-302 ng/mL
Trough: 22-177 ng/mL
The lower limit of detection for this assay is 23 ng/mL.
For additional information, please refer to www.arupconsult.com
This test was developed and its performance characteristics determined by ARUP Laboratories. It has not been cleared or approved by the US Food and Drug Administration. This test was performed in a CLIA certified laboratory and is intended for clinical purposes.
Laboratory Developed Test (LDT)
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