Preferred panel for the workup of suspected rheumatoid arthritis or undifferentiated inflammatory arthritides.
Semi-Quantitative Enzyme-Linked Immunosorbent Assay/Quantitative Immunoturbidimetry
New York DOH Approval Status
Fasting specimen preferred.
Serum separator tube.
Allow serum to clot completely at room temperature before centrifuging. Transfer 2 mL serum to an ARUP Standard Transport Tube. (Min: 1 mL) Serum is the only acceptable specimen type for this assay without a disclaimer.
Contaminated, heat-inactivated, hemolyzed, icteric, or severely lipemic specimens.
After separation from cells: Ambient: 24 hours; Refrigerated: 1 week; Frozen: 1 month (should not be thawed more than once)
|Cyclic Citrullinated Peptide Ab, IgG||0-19 Units|
|Rheumatoid Factor||0-14 IU/mL|
|Carbamylated Protein Antibody, IgG||0-19 Units|
Anticyclic citrullinated peptide (anti-CCP) IgG antibodies are present in about 69-83 percent of patients with rheumatoid arthritis (RA) and have specificities of 93-95 percent. Anticarbamylated protein (anti-CarP) IgG antibodies are present in about 34-53 percent of patients with RA, have specificities of greater than 90 percent and can occur in RA patients seronegative for both rheumatoid factor and anti-CCP. Anti-CCP and anti-CarP autoantibodies may be present in the preclinical phase of disease, are associated with future RA development, and may predict radiographic joint destruction. Patients with weak positive results should be monitored and testing repeated.
This test was developed and its performance characteristics determined by ARUP Laboratories. It has not been cleared or approved by the US Food and Drug Administration. This test was performed in a CLIA certified laboratory and is intended for clinical purposes.
|Cyclic Citrullinated Peptide (CCP) Antibody, IgG||19 Units or less
60 Units or Greater
Analyte Specific Reagent (ASR)
86200; 86431; 83516
|Component Test Code*||Component Chart Name||LOINC|
|0055256||Cyclic Citrullinated Peptide Ab, IgG||33935-8|
|3003993||Carbamylated Protein Antibody, IgG|
- Carbamylated Protein IgG
- CarP IgG
- CCP and RF
- RA Panel
- RF and CCP IgG
- Rheumatoid Arthritis Profile