Ordering Recommendation

Use to monitor and evaluate for local metal ion release from metal-on-metal joint arthroplasty, especially when multiple metal implants are investigated. Should not be used to assess toxicity.

New York DOH Approval Status

This test is not New York state approved. There are no New York state-approved laboratories available. Submit a Non-Permitted Laboratory Request Form (NPL) to the NYDOH prior to collection of specimen. If NPL is approved by NYDOH, and sample is received at ARUP, testing will be performed.

Specimen Required

Patient Preparation

Body fluid.

Specimen Preparation

Transfer 5 mL body fluid to a trace element-free transport tube (ARUP supply #43116) or acid-washed transfer vial (ARUP supply #54350) available online through eSupply using ARUP Connect (TM) or contact ARUP Client Services at 800-522-2787. (Min: 2.8 mL)

Test is not performed at ARUP; separate specimens must be submitted when multiple tests are ordered.

Storage/Transport Temperature

Refrigerated. Also acceptable: Room temperature or frozen.

Unacceptable Conditions

Ambient: Undefined; Refrigerated: Undefined; Frozen: Undefined


Quantitative Inductively Coupled Plasma-Mass Spectrometry (ICP-MS)




7-10 days

Reference Interval

By report

Interpretive Data

Compliance Category

Performed by non-ARUP Laboratory


Hotline History


CPT Codes

82495; 83018 x 2


Component Test Code* Component Chart Name LOINC
3003914 Chromium, Body Fluid 21199-5
3003915 Cobalt, Body Fluid 51194-9
3003916 Titanium, Body Fluid 51210-3
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.


Orthopedic Metals Panel (Chromium, Cobalt, Titanium), Body Fluid

National Medical Services (NMS)