Use to evaluate response failure to vedolizumab therapy. Use to adjust dosage.
Quantitative Liquid Chromatography/Mass Spectrometry (LC-MS/MS) /Electrochemiluminescent Immunoassay
New York DOH Approval Status
12 hours prior to specimen collection discontinue multivitamins or dietary supplements containing biotin (vitamin B7), commonly found in hair, skin, and nail supplements. Nivolumab (Opdivo) must be discontinued at least 4 weeks prior to testing.
Plain red. Also acceptable: Serum separator tube (SST). Collect immediately before next scheduled dose (trough specimen).
Separate from cells ASAP or within 2 hours of collection. Transfer 1.5 mL serum to an ARUP Standard Transport Tube. (Min: 0.75 mL)
Test is not performed at ARUP; separate specimens must be submitted when multiple tests are ordered.
Refrigerated. Also acceptable: Frozen.
Ambient: Unacceptable; Refrigerated: 28 days; Frozen: 28 days
|Component Test Code*||Component Chart Name||LOINC|
|3003677||Vedolizumab Quantitation, Serum||90805-3|
|3003678||Vedolizumab Antibodies, Serum||86899-2|
Mayo Clinic Laboratories