Mucopolysaccharidoses Type 1/2, Total Heparan Sulfate and NRE (Sensi-Pro®) Quantitative, Serum or Plasma
Ordering Recommendation
Aids in the diagnosis and monitoring of patients with MPS Type 1 or Type 2.
Methodology
Liquid Chromatography-Tandem Mass Spectrometry
Performed
Varies
Reported
14-21 days
New York DOH Approval Status
Specimen Required
Lavender (K2EDTA, K3EDTA), Plain Red, or Serum Separator Tube (SST).
Transfer 500 µL serum or plasma to ARUP Standard transport Tube and freeze immediately. (Min 250 µL)
Critical Frozen
Plasma collected in green (heparin) tube. Ambient or Refrigerated Specimens
Ambient: Unacceptable; Refrigerated: Unacceptable; Frozen: 1 month (avoid repeated freeze /thaw cycles)
Reference Interval
By report
Interpretive Data
Total Heparan Sulfate, Serum/Plasma is a sum of the internal disaccharides D0A0 and D0S0.
NRE = Non Reducing End
This test was developed and its performance characteristics determined by ARUP Laboratories. It has not been cleared or approved by the US Food and Drug Administration. This test was performed in a CLIA certified laboratory and is intended for clinical purposes.
Laboratory Developed Test (LDT)
Note
Hotline History
Hotline History
CPT Codes
83864
Components
Component Test Code* | Component Chart Name | LOINC |
---|---|---|
3003567 | MPS 1/2 Serum/Plasma Interpretation | 59462-2 |
3003570 | Total Heparan Sulfate, Serum/Plasma | 93725-0 |
3003571 | I0S0 (MPS 1 NRE), Serum/Plasma | |
3003572 | I0S6 (MPS 1 NRE), Serum/Plasma | |
3003573 | I2S0 (MPS 2 NRE), Serum/Plasma | |
3005211 | EER MPS 1/2 Serum/Plasma | 11502-2 |
Aliases
- Heparan Sulfate total and NRE, Serum/Plasma
- HS non reducing end assay
- MPS 1
- MPS 2
- MPS I
- MPS II
- MPS Type 1
- MPS Type 2