Mucopolysaccharidoses Type 1/2, Total Heparan Sulfate and NRE (Sensi-Pro®) Quantitative, Serum or Plasma
Aids in the diagnosis and monitoring of patients with MPS Type 1 or Type 2.
Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)
Lavender (K2EDTA, K3EDTA), Plain Red, or Serum Separator Tube (SST).
Transfer 500 µL serum or plasma to ARUP Standard transport Tube and freeze immediately. (Min 250 µL)
Plasma collected in green (heparin) tube. Ambient or Refrigerated Specimens
Ambient: Unacceptable; Refrigerated: Unacceptable; Frozen: 1 month (avoid repeated freeze /thaw cycles)
Total Heparan Sulfate, Serum/Plasma is a sum of the internal disaccharides D0A0 and D0S0.
NRE = Non Reducing End
This test was developed and its performance characteristics determined by ARUP Laboratories. It has not been cleared or approved by the US Food and Drug Administration. This test was performed in a CLIA certified laboratory and is intended for clinical purposes.
Laboratory Developed Test (LDT)
|Component Test Code*||Component Chart Name||LOINC|
|3003567||MPS 1/2 Serum/Plasma Interpretation||59462-2|
|3003570||Total Heparan Sulfate, Serum/Plasma||93725-0|
|3003571||I0S0 (MPS 1 NRE), Serum/Plasma|
|3003572||I0S6 (MPS 1 NRE), Serum/Plasma|
|3003573||I2S0 (MPS 2 NRE), Serum/Plasma|
- Heparan Sulfate total and NRE, Serum/Plasma
- HS non reducing end assay
- MPS 1
- MPS 2
- MPS I
- MPS II
- MPS Type 1
- MPS Type 2