Mucopolysaccharidoses Type 4A/6 Total Chondroitin Sulfate and Dermatan Sulfate with NRE (Sensi-Pro®) Quantitative, Urine

3003539
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Mucopolysaccharides (MPS) Testing Patient History Form

Ordering Recommendation

Aids in the diagnosis and monitoring of patients with MPS Type 4A or Type 6.

Mnemonic

MPS 4A/6 U

Methodology

Liquid Chromatography-Tandem Mass Spectrometry

Performed

Varies

Reported

2-3 weeks

New York DOH Approval Status

Specimens from New York clients will be sent out to a New York DOH approved laboratory, if possible.

Specimen Required

Patient Preparation

N/A

Collect

Urine

Specimen Preparation

Transfer 0.25 mL urine to polypropylene sample tube and freeze immediately. (Min 0.15 mL)

Storage/Transport Temperature

Critical Frozen

Unacceptable Conditions

Specimens containing preservatives or heparin

Remarks

N/A

Stability

Ambient: Unacceptable; Refrigerated: Unacceptable; Frozen: 1 year (3 freeze thaw cycles are acceptable)

Reference Interval

By report

Interpretive Data

Refer to report.
Total Chondroitin Sulfate and Dermatan Sulfate, Urine is a sum of the internal disaccharides D0a0, D0a4, and D0a6.
NRE = Non Reducing End

This test was developed and its performance characteristics determined by ARUP Laboratories. It has not been cleared or approved by the US Food and Drug Administration. This test was performed in a CLIA certified laboratory and is intended for clinical purposes.

Compliance Category

Laboratory Developed Test (LDT)

Note

Hotline History

View Hotline History

 

Hotline History

Date of Change
Test Name Change
Methodology
Performance/Reported Schedule
Specimen Requirements
Reference Interval
Interpretive Data
Note
CPT Code
Component Change
Other Interface Change
New Test
Inactive
08/15/2022
X
12/24/2020
X
N/A

CPT Codes

83864

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Components

Component Test Code* Component Chart Name LOINC
3003540 MPS 4A/6 Creatinine, Urine
3003541 MPS 4A/6 Urine Interpretation
3003546 Chondroitin and Dermatan Sulfate, Urine
3003548 a4 (MPS 6 NRE), Urine
3003550 a6 (MPS 4A NRE), Urine
3003551 a4/a6 Ratio, Urine
3005209 EER MPS 4A/6 Urine 11502-2
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.

Aliases

  • CS non-reducing end assay
  • DS non-reducing end assay
  • MPS 4a
  • MPS 6
  • MPS type 4a
  • MPS type 6
  • Mucopolysaccharides
  • Total Chondroitin Sulfate
  • Total Dermatan Sulfate
Mucopolysaccharidoses Type 4A/6 Total Chondroitin Sulfate and Dermatan Sulfate with NRE (Sensi-Pro(R)) Quantitative, Urine