Mucopolysaccharidoses Type 4A/6 Total Chondroitin Sulfate and Dermatan Sulfate with NRE (Sensi-Pro®) Quantitative, Serum
Aids in the diagnosis and monitoring of patients with MPS Type 4A or Type 6.
Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)
New York DOH Approval Status
Serum (Serum Separator Tube (SST)).
Transfer 500 µL serum to ARUP Standard transport Tube and freeze immediately. (Min 300 µL)
Ambient: Unacceptable; Refrigerated: 1 week; Frozen: 4 month (3 freeze thaw cycles are acceptable)
Total Chondroitin Sulfate (CS) and Dermatan Sulfate (DS), Serum is a sum of the internal disaccharides D0a0, D0a4, and D0a6.
NRE = Non Reducing End
This test was developed, and its performance characteristics determined by ARUP Laboratories. It has not been cleared or approved by the US Food and Drug Administration. This test was performed in a CLIA certified laboratory and is intended for clinical purposes.
Laboratory Developed Test (LDT)
|Component Test Code*||Component Chart Name||LOINC|
|3003488||MPS 4A/6, Serum Interpretation||59462-2|
|3003492||Chondroitin and Dermatan Sulfate, Serum|
|3003493||a4 (MPS 6 NRE), Serum|
|3003494||a6 (MPS 4A NRE), Serum|
|3003495||a4/a6 Ratio, Serum|
- CS non reducing end assay
- DS non reducing end assay
- MPS 4a
- MPS 6
- MPS type 4a
- MPS type 6
- Total Chondroitin Sulfate
- Total Dermatan Sulfate