Ordering Recommendation

Recommended autoantibody panel for the evaluation of patients at risk for membranous nephropathy.

New York DOH Approval Status

This test is New York state approved.

Specimen Required

Patient Preparation

Serum Separator Tube

Specimen Preparation

Separate serum from cells ASAP or within 2 hours of collection. Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.2 mL)

Storage/Transport Temperature


Unacceptable Conditions

Hemolyzed, hyperlipemic, icteric, heat-treated or contaminated


Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 month


Semi-Quantitative Indirect Fluorescent Antibody




1-8 days

Reference Interval

Test Number
Reference Interval
  Phospholipase A2 Receptor, IgG Less than 1:10
  THSD7A Ab, IgG, Screen Less than 1:10

Interpretive Data

Refer to individual components.

This test was developed and its performance characteristics determined by ARUP Laboratories. It has not been cleared or approved by the US Food and Drug Administration. This test was performed in a CLIA certified laboratory and is intended for clinical purposes.

Compliance Category

Laboratory Developed Test (LDT)


If Phospholipase A2 Receptor Antibody, IgG is positive, then a Phospholipase Receptor A2 Antibody, IgG titer will be added. Additional charges apply. If THSD7A Antibody, IgG is positive, then a THSD7A Antibody, IgG titer will be added.. Additional charges apply.

Hotline History


CPT Codes

86255 x2; if reflexed, add 86256 x2


Component Test Code* Component Chart Name LOINC
2011829 Phospholipase A2 Receptor, IgG 82991-1
3003478 THSD7A Ab, IgG, Screen 93339-0
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.


Membranous Nephropathy Comprehensive Autoantibody Panel