Ordering Recommendation

Aids in identification of patients with essential fatty acid deficiency, evaluation of nutritional status, and diet monitoring.

New York DOH Approval Status

This test is New York state approved.

Specimen Required

Patient Preparation

Green (sodium heparin), lavender (K2EDTA), or yellow (ACD solution A).

Specimen Preparation

DO NOT FREEZE. Transport 6 mL whole blood. (Min: 2 mL)

Storage/Transport Temperature


Unacceptable Conditions

Gross hemolysis, frozen whole blood.


Patient age is required on the test request form. Include information regarding treatment, family history, and tentative diagnosis.


Ambient: 24 hours; Refrigerated: 7 days; Frozen: Unacceptable


Gas Chromatography-Mass Spectrometry (GC-MS)




7-10 days

Reference Interval

By Report

Interpretive Data

This test does not screen for disorders of peroxisomal biogenesis/function.

Compliance Category

Laboratory Developed Test (LDT)


Hotline History


CPT Codes



Component Test Code* Component Chart Name LOINC
3003087 Interpretation, Fatty Acids Profile RBC 75114-9
3003088 Myristic Acid, C14:0, RBC 75103-2
3003089 Palmitic Acid, C16:0, RBC 75115-6
3003090 Stearic Acid, C18:0, RBC 75118-0
3003091 Arachidic Acid, C20:0, RBC 75108-1
3003092 Palmitoleic Acid, C16:1w7, RBC 75111-5
3003093 Hexadecenoic Acid, C16:1w9, RBC 78346-4
3003094 Vaccenic Acid, C18:1w7, RBC 78352-2
3003095 a-Linolenic Acid, C18:3w3, RBC 75113-1
3003096 EPA, C20:5w3, RBC 75097-6
3003097 DPA, C22:5w3, RBC 78347-2
3003098 DHA, C22:6w3, RBC 75095-0
3003099 Linoleic Acid, C18:2w6, RBC 75117-2
3003100 g-Linolenic Acid, C18:3w6, RBC 75119-8
3003101 h-g-Linolenic C20:3w6, RBC 79704-3
3003102 Arachidonic Acid, C20:4w6, RBC 75110-7
3003103 DTA, C22:4w6, RBC 75112-3
3003104 DPA, C22:5w6, RBC 78348-0
3003105 Oleic Acid, C18:1w9, RBC 75102-4
3003106 Mead Acid, C20:3w9, RBC 75106-5
3003107 Docosenoic Acid, C22:1, RBC 78345-6
3003108 Nervonic Acid, C24:1w9, RBC 75098-4
3003109 Triene Tetraene Ratio, RBC 99616-5
3003110 Total Saturated Acid, RBC 99617-3
3003111 Total Monounsaturated Acid, RBC 99618-1
3003112 Total Polyunsaturated Acid, RBC 99619-9
3003113 Total w3, RBC 99620-7
3003114 Total w6, RBC 99621-5
3003115 Total Fatty Acids, RBC 75100-8
3003116 EER Fatty Acids Profile, Essential RBC 11502-2
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.


Fatty Acids Profile, Essential in Red Blood Cells