Comprehensive panel for the evaluation of paraneoplastic and neuromuscular junction disorders, and/or encephalitis, in the presence or absence of malignancy.
Semi-Quantitative Indirect Fluorescent Antibody/Qualitative Immunoblot/Quantitative Radioimmunoassay/Semi-Quantitative Enzyme-Linked Immunosorbent Assay
Tue
3-10 days
Serum Separator Tube (SST)
Separate from cells ASAP or within 2 hours of collection. Transfer three 1 mL serum aliquots to ARUP Standard Transport Tubes. (Min: 0.5 mL/aliquot)
Frozen
Amniotic fluid, ocular fluid, peritoneal fluid, synovial fluid, CSF, or plasma. Contaminated, hemolyzed, icteric, or lipemic specimens.
After separation from cells: Ambient: 24 hours; Refrigerated: 1 week; Frozen: 1 month (avoid repeated freeze/thaw cycles)
Test Number |
Components |
Reference Interval |
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0050746 | Striated Muscle Antibodies, IgG with Reflex to Titer | Less than 1:40 | |||||||||||||||
2004221 | N-methyl-D-Aspartate Receptor Antibody, IgG, Serum with Reflex to Titer | < 1:10 | |||||||||||||||
2001771 | Glutamic Acid Decarboxylase Antibody | 0.0-5.0 IU/mL | |||||||||||||||
2013956 | CV2.1 Screen by IFA with Reflex to Titer | Less than 1:10 | |||||||||||||||
0092628 | P/Q-Type Voltage-Gated Calcium Channel (VGCC) Antibody | Effective November 14, 2011
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2005636 | Titin Antibody | Effective January 17, 2012
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2004890 | Voltage-Gated Potassium Channel (VGKC) Antibody, Serum |
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2003036 | Aquaporin-4 Receptor Antibody | Effective October 3, 2016
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0080009 | Acetylcholine Receptor Binding Antibody |
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2007961 | Paraneoplastic Antibodies (PCCA/ANNA) by IFA with Reflex to Titer and Immunoblot | Effective August 17, 2020
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2008893 | Amphiphysin Antibody, IgG | Negative | |||||||||||||||
2013320 | Aquaporin-4 Receptor Antibody, IgG by IFA with Reflex to Titer, Serum | Less than 1:10 | |||||||||||||||
2009456 | Leucine-Rich, Glioma-Inactivated Protein 1 Antibody, IgG with Reflex to Titer, Serum | Less than 1:10 | |||||||||||||||
2009452 | Contactin-Associated Protein-2 Antibody, IgG with Reflex to Titer, Serum | Less than 1:10 | |||||||||||||||
0099521 | Acetylcholine Receptor Modulating Antibody | Effective August 20, 2012
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N-Type Calcium Channel Antibody |
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3001260 | Alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid (AMPA) Receptor Antibody, IgG by IFA with Reflex to Titer, Serum | Less than 1:10 | |||||||||||||||
3001270 | Gamma Aminobutyric Acid Receptor, Type B (GABA-BR) Antibody, IgG by IFA with Reflex to Titer, Serum | Less than 1:10 | |||||||||||||||
3001277 | Myelin Oligodendrocyte Glycoprotein (MOG) Antibody, IgG by IFA with Reflex to Titer, Serum | Less than 1:10 | |||||||||||||||
3002885 | SOX1 Antibody, IgG by Immunoblot, Serum | Negative | |||||||||||||||
3003020 | Ganglionic Acetylcholine Receptor Antibody |
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Refer to Report
Analyte Specific Reagent (ASR)
If Striated Muscle Ab is detected, then a titer will be added. Additional charges apply.
If N-methyl-D-Aspartate Receptor Antibody is positive, then titer will be added. Additional charges apply.
If CV2.1 Antibody IgG Screen by IFA is positive, then a titer will be added. Additional charges apply.
If Aquaporin-4 Receptor Antibody IgG by ELISA is positive, then Aquaporin-4 Receptor Antibody, IgG by IFA will be added. If positive, then a titer will be added. Additional charges apply.
If Acetylcholine Receptor Binding Antibody result is greater than 0.4 nmol/L then Acetylcholine Receptor Modulating Antibody will be added. Additional charges apply.
Purkinje Cell (PCCA) antibody and Neuronal Nuclear (ANNA) antibody IgG are screened by IFA. If the IFA screen is indeterminate, then a Neuronal Nuclear Antibodies (Hu, Ri, Yo, and Tr/DNER) IgG by Immunoblot will be added. If the IFA screen is positive at 1:10 or greater, then a PCCA/ANNA antibodies titer and Neuronal Nuclear Antibodies (Hu, Ri, Yo, Tr/DNER) IgG by Immunoblot will be added. Additional charges apply.
If LGI1 antibody IgG is positive, then LGI1 antibody IgG titer will be added. Additional charges apply.
If CASPR2 antibody IgG is positive, then CASPR2 antibody IgG titer will be added. Additional charges apply.
If Alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid (AMPA) Receptor Antibody, IgG by IFA with Reflex to Titer, Serum is positive, then an Alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid (AMPA) Receptor Antibody Titer, IgG, Serum is reported. Additional charges apply.
If Gamma Aminobutyric Acid Receptor, Type B (GABA-BR) Antibody, IgG by IFA with Reflex to Titer, Serum is positive, then a Gamma Aminobutyric Acid Receptor, Type B (GABA-BR) Antibody Titer, IgG, Serum is performed. Additional charges apply.
If Myelin Oligodendrocyte Glycoprotein (MOG) Antibody, IgG by IFA with Reflex to Titer, Serum is positive, then a Myelin Oligodendrocyte Glycoprotein (MOG) Antibody Titer, IgG is performed. Additional charges apply.
Hotline History
83519 x5; 83516 x2; 84182 x2; 86255 x9; 86341; if reflexed, additional CPT codes may apply: 83516; 86255; 86256; 84182 x4
Component Test Code* | Component Chart Name | LOINC |
---|---|---|
0050747 | Striated Muscle Antibodies, IgG Screen | 49692-7 |
0051709 | Neuronal Antibody (Amphiphysin) | 94385-2 |
0080009 | Acetylcholine Binding Antibody | 11034-6 |
0092629 | P/Q-Type Calcium Channel Antibody | 33980-4 |
2001772 | Glutamic Acid Decarboxylase Antibody | 56540-8 |
2003121 | Aquaporin-4 Receptor Antibody | 68548-7 |
2004222 | N-methyl-D-Aspartate Receptor Ab, Serum | 80221-5 |
2004890 | Voltage-Gated Potassium Channel Ab, Ser | 41871-5 |
2005637 | Titin Antibody | |
2007962 | Purkinje Cell/Neuronal Nuclear IgG Scrn | 61177-2 |
2009453 | CASPR2 Ab IgG Screen by IFA, Serum | 82979-6 |
2009457 | LGI1 Ab IgG Screen by IFA, Serum | 82978-8 |
2013959 | CV2.1 Antibody IgG Screen by IFA | 72504-4 |
3001261 | AMPA Receptor Ab IgG Screen, Serum | 82733-7 |
3001271 | GABA-B Receptor Ab IgG Screen, Serum | 93428-1 |
3001278 | MOG Antibody IgG Screen, Serum | 91545-4 |
3002047 | N-Type Calcium Channel Antibody | 33979-6 |
3002903 | SOX1 Antibody, IgG by Immunoblot, Serum | 82444-1 |
3003019 | Ganglionic Acetylcholine Receptor Ab | 42233-7 |