Ordering Recommendation

Use to monitor cyanide exposure.

New York DOH Approval Status

This test is New York state approved.

Specimen Required

Patient Preparation

Gray top tube (Sodium Fluoride / Potassium Oxalate)

Specimen Preparation

1 mL whole blood. (Min: 0.4 mL)
Test is not performed at ARUP; separate specimens must be submitted when multiple tests are ordered.

Storage/Transport Temperature

Refrigerated. Also acceptable: Frozen.

Unacceptable Conditions

Ambient: Undefined; Refrigerated: 1 week; Frozen: 3 months


Quantitative High Performance Liquid Chromatography-Tandem Mass Spectrometry




8-11 days

Reference Interval

By report

Interpretive Data

Compliance Category

Performed by non-ARUP Laboratory


Studies have shown that cyanide has variable instability in biological specimens and is particularly unstable in some postmortem specimens. The loss of cyanide can be minimized by shipping the sample to the laboratory for analysis as soon as possible, preferably using refrigerated or frozen transportation and preservation using sodium fluoride/potassium oxalate (grey-top tube). The potential for increases in cyanide concentrations, although rare, have also been demonstrated and may be due to microbial action. Preservation with sodium fluoride may reduce this possibility.

Hotline History


CPT Codes



Component Test Code* Component Chart Name LOINC
3003040 Cyanide, Whole Blood 5634-1
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.


  • CN
  • Hydrogen Cyanide
  • Potassium Cyanide
Cyanide, Whole Blood

National Medical Services (NMS)