Ordering Recommendation

Use to detect Epstein-Barr virus in paraffin. Includes interpretation.

Mnemonic

EBVP ISH

Methodology

In situ hybridization (ISH)

Performed

Mon-Fri

Reported

2-5 days

New York DOH Approval Status

This test is New York DOH approved.

Specimen Required

Patient Preparation
Collect

Tissue.

Specimen Preparation

Formalin fix (10% neutral buffered formalin) and paraffin-embed tissue. Transport tissue block or 5 unstained 5 micron slides. (Min: 4 slides) Protect paraffin block and/or slides from excessive heat.

Storage/Transport Temperature

Room temperature. Also acceptable: Refrigerated. Ship in cooled container during summer months.

Unacceptable Conditions

Specimens fixed or processed in alternative fixatives (alcohol, Prefer®) or heavy metal fixatives (B-4 or B-5).

Remarks

Include surgical pathology report.
If multiple specimens (blocks or slides) are sent to ARUP, they must be accompanied by one of the following: an order comment indicating that the ARUP pathologist should choose the specimen most appropriate for testing (e.g., "Choose best block"), or individual orders for each sample submitted. A Pathologist Block Selection Fee (ARUP test code 3002076) will be added to orders that utilize the first option. If multiple specimens are sent to ARUP without a request for pathologist block/slide selection or individual orders, they will be held until clarification is provided.

Stability

Ambient: Indefinitely; Refrigerated: Indefinitely; Frozen: Unacceptable

Reference Interval

Negative

Interpretive Data

Refer to report

Compliance Category

Note

Hotline History

N/A

CPT Codes

88365

Components

Component Test Code* Component Chart Name LOINC
3003235 H and E Slide Description
3003236 Epstein-Barr Virus (EBV) ISH Result
3003237 EBV ISH Comment
3003240 ISH Reference Number
3003241 ISH Tissue Source
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.

Aliases

  • EBER ISH
  • EBV by ISH
  • EBV ISH
Epstein-Barr Virus (EBV) by in situ Hybridization on Paraffin