Detects antibodies during acute phase; paired concurrent specimen with IgG reduces false positive rate. Convalescent sera may be required for diagnosis.
Semi-Quantitative Enzyme-Linked Immunosorbent Assay
Mon, Wed, Fri
Serum separator tube (SST) or Plain Red/Red-Top.
Separate serum from cells ASAP or within 2 hours of collection. Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.6 mL)
Contaminated, heat-inactivated, or turbid specimens.
After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 month
|9 U/mL or less||Negative - No significant level of IgM antibody to Francisella tularensis detected.|
|10-15 U/mL||Equivocal - Questionable presence of IgM antibody to Francisella tularensis. Repeat testing in 10-14 days may be helpful.|
|16 U/mL or greater||Positive - Presence of IgM antibody to Francisella tularensis detected, suggestive of current or recent exposure/immunization.|
Cross-reactivity with Brucella and Yersinia antibodies may occur. Therefore, results should be interpreted with caution and correlated with clinical information. The best evidence for current infection is a significant change on two appropriately timed specimens, where both tests are performed in the same laboratory at the same time.
Laboratory Developed Test (LDT)
If the ELISA testing is equivocal or positive, then Francisella tularensis Antibodies by Agglutination will be added. Additional charges apply.
86668; if reflexed add 86000
|Component Test Code*||Component Chart Name||LOINC|
|2005352||Francisella tularensis Antibody, IgM||16878-1|
- F. tularensis IgM
- Francisella Antibodies
- Francisella Tularensis Ab