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Francisella tularensis Antibodies, IgG and IgM with Reflex to Agglutination

FTULARPANR
Example Reports
Negative
Positive

Ordering Recommendation

Preferred test for detecting antibodies during acute or convalescent phase. Convalescent sera may be required for diagnosis.

New York DOH Approval Status

This test is New York state approved.

Specimen Required

Patient Preparation
Collect

Serum separator tube (SST) or plain red/red top

Specimen Preparation

Separate serum from cells ASAP or within 2 hours of collection. Transfer 1 mL serum to an ARUP standard transport tube. (Min: 0.6 mL)

Storage/Transport Temperature

Refrigerated.

Unacceptable Conditions

Contaminated, heat-inactivated, or turbid specimens.

Remarks
Stability

After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 month

Methodology

Semi-Quantitative Enzyme-Linked Immunosorbent Assay

Performed

Mon, Wed, Fri

Reported

1-6 days

Reference Interval

Test Number
 Components
 Reference Interval
  Francisella tularensis Antibody, IgG 9 U/mL or less
  Francisella tularensis Antibody, IgM 9 U/mL or less

Interpretive Data

Cross-reactivity with Brucella and Yersinia antibodies may occur. False-positive results are possible, therefore results should be interpreted with caution and correlated with clinical information. Confirmation by another method, such as agglutination may be helpful.


Component
Interpretation
Francisella tularensis Antibody, IgG 9 U/mL or less  Negative: No significant level of IgG antibody to Francisella tularensis detected.
10-15 U/mL  Equivocal: Questionable presence of IgG antibody to Francisella tularensis. Repeat testing in 10-14 days may be helpful.
16 U/mL or greater  Positive: Presence of IgG antibody to Francisella tularensis detected, suggestive of current or past exposure.
Francisella tularensis Antibody, IgM 9 U/mL or less  Negative: No significant level of IgM antibody to Francisella tularensis detected.
10-15 U/mL  Equivocal: Questionable presence of IgM antibody to Francisella tularensis. Repeat testing in 10-14 days may be helpful.
16 U/mL or greater  Positive: Presence of IgM antibody to Francisella tularensis detected, suggestive of recent infection.

Compliance Category

Laboratory Developed Test (LDT)

Note

If the ELISA testing is equivocal or positive for IgG and/or IgM, then Francisella tularensis Antibodies by Agglutination will be added. Additional charges apply.

Hotline History

N/A

CPT Codes

86668 x2, if reflexed add 86000

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Components

Component Test Code* Component Chart Name LOINC
2005351 Francisella tularensis Antibody, IgG 70121-9
2005352 Francisella tularensis Antibody, IgM 16878-1
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.

Aliases

  • F. tularensis IgG, IgM
  • Febrile Antigens
  • Francisella Antibodies
  • Francisella Tularensis Ab
Francisella tularensis Antibodies, IgG and IgM with Reflex to Agglutination