SOX1 Antibody, IgG by Immunoblot, CSF

3002886
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Example Reports
Negative
Positive

Ordering Recommendation

Consider ordering for individuals with Lambert-Eaton myasthenic syndrome (LEMS), paraneoplastic cerebellar degeneration (PCD), or paraneoplastic and nonparaneoplastic neuronopathy. May aid in the diagnosis of occult tumor, recurrence of tumor, or second tumor. Serum is the preferred specimen type; see SOX1 Antibody, IgG by Immunoblot, Serum (3002885).

Mnemonic

SOX1 CSF

Methodology

Qualitative Immunoblot

Performed

Mon, Thu, Sat

Reported

1-4 days

New York DOH Approval Status

This test is New York DOH approved.

Specimen Required

Patient Preparation
Collect

CSF

Specimen Preparation

Transfer 1 mL CSF to an ARUP Standard Transport Tube. (Min: 0.60 mL)

Storage/Transport Temperature

Refrigerated.

Unacceptable Conditions

Contaminated, heat-inactivated, hemolyzed, or lipemic specimens.

Remarks
Stability

Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 month

Reference Interval

Negative

Interpretive Data

SOX1 antibody is detected in patients with Lambert-Eaton myasthenic syndrome (LEMS) and in patients with paraneoplastic cerebellar degeneration (PCD), paraneoplastic and nonparaneoplastic neuropathy. SOX1 antibody is associated with small cell lung cancer. A negative test result does not rule out a diagnosis of LEMS or other causes of paraneoplastic neurological syndrome.

Compliance Category

Laboratory Developed Test (LDT)

Note

Hotline History

View Hotline History

 

Hotline History

Date of Change
Test Name Change
Methodology
Performance/Reported Schedule
Specimen Requirements
Reference Interval
Interpretive Data
Note
CPT Code
Component Change
Other Interface Change
New Test
Inactive
08/17/2020
X
N/A

CPT Codes

84182

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Components

Component Test Code* Component Chart Name LOINC
3002904 SOX1 Antibody, IgG by Immunoblot, CSF
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.

Aliases

SOX1 Antibody, IgG by Immunoblot, CSF