Hereditary Melanoma Panel, Sequencing and Deletion/Duplication
Recommended test to confirm a hereditary cause of melanoma in individuals with a personal or family history of disease. Testing minors for adult-onset conditions is not recommended; testing will not be performed in minors without prior approval. For additional information, please contact an ARUP genetic counselor at 800-242-2787 ext. 2141.
To compare this test to other hereditary cancer panels, refer to the ARUP Hereditary Cancer Panel Comparison table.
New York DOH Approval Status
Lavender or pink (EDTA) or yellow (ACD solution A or B).
New York State Clients: Lavender (EDTA)
Transport 3 mL whole blood. (Min: 2 mL)
New York State Clients: 5 mL (Min: 2 mL)
Serum or plasma; grossly hemolyzed or frozen specimens; saliva; buccal brush, or swab; FFPE tissue.
Ambient: 72 hours; Refrigerated: 1 week; Frozen: Unacceptable
New York State Clients: Ambient: 24 hours; Refrigerated: 1 week; Frozen: Unacceptable
Massively Parallel Sequencing/Sequencing
Refer to report.
Laboratory Developed Test (LDT)
GENES TESTED: BAP1; BRCA2; CDK4; CDKN2A*; MC1R; MITF*; POT1; PTEN*; RB1*; TERT; TP53
*One or more exons are not covered by sequencing and/or deletion/duplication analysis for the indicated gene; see Additional Technical Information.
81167; 81216; 81404; 81321; 81323; 81351; 81479
|Component Test Code*||Component Chart Name||LOINC|
- Cowden syndrome
- Dyskeratosis congenita
- FAMMM syndrome
- Hereditary retinoblastoma
- Li-Fraumeni syndrome
- Melanoma, Familial melanoma, Familial atypical multiple mole melanoma