Ordering Recommendation
Initial screening for suspected deficiency in the classical complement pathway.
Mnemonic
CH50 TOTAL
Methodology
Quantitative Immunoturbidimetry
Performed
Sun-Sat
Reported
1-2 days
New York DOH Approval Status
This test is New York DOH approved.
Specimen Required
Patient Preparation
Collect
Plain red.
Specimen Preparation
Allow specimen to clot for one hour at room temperature. Separate serum from cells ASAP or within 2 hours of collection. Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.5 mL)
Storage/Transport Temperature
CRITICAL FROZEN. Separate specimens must be submitted when multiple tests are ordered.
Unacceptable Conditions
Separator tubes. Specimens left to clot at 2-8°C. Specimens exposed to repeated freeze/thaw cycles. Non-frozen specimens. Grossly hemolyzed or severely lipemic specimens.
Remarks
Stability
After separation from cells: Ambient: Unacceptable; Refrigerated: Unacceptable; Frozen: 1 month
Reference Interval
Low | 38.6 U/mL or less |
Normal | 38.7-89.9 U/mL |
High | 90.0 U/mL or greater |
Interpretive Data
Compliance Category
FDA
Note
Hotline History
N/A
CPT Codes
86162
Components
Component Test Code* | Component Chart Name | LOINC |
---|---|---|
3002576 | Complement Activity, Total Turbidimetric | 4532-8 |
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
- CAE
- CAE total
- CH50
- Complement CH100, Total
- Total Complement
- Total Complement CH100
- Total Complement CH50
- Total Hemolytic Complement Activity
Complement Activity Total, (CH50)