Ordering Recommendation

Initial screening for suspected deficiency in the classical complement pathway.

Mnemonic
CH50 TOTAL
Methodology

Quantitative Immunoturbidimetry

Performed

Sun-Sat

Reported

1-2 days

New York DOH Approval Status
This test is New York DOH approved.
Specimen Required
Patient Preparation
Collect

Plain red.

Specimen Preparation

Allow specimen to clot for one hour at room temperature. Separate serum from cells ASAP or within 2 hours of collection. Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.5 mL)

Storage/Transport Temperature

CRITICAL FROZEN. Separate specimens must be submitted when multiple tests are ordered.

Unacceptable Conditions

Separator tubes. Specimens left to clot at 2-8°C. Specimens exposed to repeated freeze/thaw cycles. Non-frozen specimens. Grossly hemolyzed or severely lipemic specimens.

Remarks
Stability

After separation from cells: Ambient: Unacceptable; Refrigerated: Unacceptable; Frozen: 1 month

Reference Interval
Low 38.6 U/mL or less
Normal 38.7-89.9 U/mL
High 90.0 U/mL or greater

Interpretive Data



Compliance Category

FDA

Note
Hotline History
N/A
CPT Codes

86162

Components
Component Test Code* Component Chart Name LOINC
3002576 Complement Activity, Total Turbidimetric 4532-8
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • CAE
  • CAE total
  • CH50
  • Complement CH100, Total
  • Total Complement
  • Total Complement CH100
  • Total Complement CH50
  • Total Hemolytic Complement Activity
Complement Activity Total, (CH50)