Recommended for the evaluation of individuals with suspected primary biliary cholangitis (PBC) who test negative for anti-mitochondrial antibodies (AMA).
Semi-Quantitative Enzyme-Linked Immunosorbent Assay
Serum Separator Tube (SST).
Separate serum from cells ASAP or within 2 hours of collection. Transfer 0.5 mL serum to ARUP Standard Transport Tube. (Min: 0.1 mL)
Non-serum, heat-inactivated, contaminated, grossly icteric, severely lipemic, grossly hemolyzed specimens or inclusion of fibrin clot.
After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 month (avoid repeated freeze/thaw cycles)
|20.0 Units or less||Negative|
|25.0 Units or greater||Positive|
GP210 IgG antibodies can be detected in patients with primary biliary cholangitis (PBC) and may be of diagnostic relevance in a subset of patients with PBC who are negative for anti-mitochondrial antibodies (AMA). These antibodies have a relatively low sensitivity with excellent specificity for PBC. A negative result does not rule out PBC.
|Component Test Code*||Component Chart Name||LOINC|
|3002483||Anti-gp210 Antibody, IgG|