Ordering Recommendation

Acceptable test for autoimmune thyroid disease.

Mnemonic
TSIG
Methodology

Semi-Quantitative Chemiluminescent Immunoassay

Performed

Sun-Sat

Reported

Within 24 hours

New York DOH Approval Status
This test is New York DOH approved.
Specimen Required
Patient Preparation
Collect

Serum Separator Tube (SST), Green (Lithium Heparin), or Lavender (K EDTA).

Specimen Preparation

Allow specimen to clot completely at room temperature. Separate from cells ASAP or within 2 hours of collection. Transfer 1 mL serum or plasma to an ARUP Standard Transport Tube. (Min: 0.5 mL)

Storage/Transport Temperature

Frozen.

Unacceptable Conditions
Remarks
Stability

After separation from cells: Ambient: 24 hours; Refrigerated: 1 week; Frozen: 1 year

Reference Interval
0.54 IU/L or less Consistent with healthy thyroid function or non-Graves thyroid or autoimmune disease. Those with healthy thyroid function typically have results less than 0.1 IU/L.
0.55 IU/L or greater Consistent with Graves disease (autoimmune hyperthyroidism).

Interpretive Data

This assay specifically detects thyroid stimulating autoantibodies. For diagnostic purposes, the results obtained from this assay should be used in combination with clinical examination, patient medical history, and other findings.

No compliance statements are in use for this test.

Note
Hotline History
N/A
CPT Codes

84445

Components
Component Test Code* Component Chart Name LOINC
3002288 Thyroid Stimulating Immunoglobulin-TSI 30567-2
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • Autoimmune Thyroid Stimulator
  • Thyroid Stimulating Antibody
  • Thyroid-Stimulating Immunoglobulin Serum
  • TSI
  • TSI concentration
Thyroid Stimulating Immunoglobulin