Ordering Recommendation
Acceptable test secondary for autoimmune thyroid disease.
Mnemonic
TSIG
Methodology
Semi-Quantitative Chemiluminescent Immunoassay
Performed
Sun-Sat
Reported
Within 24 hours
New York DOH Approval Status
This test is New York DOH approved.
Specimen Required
Patient Preparation
Collect
Serum Separator Tube (SST), Green (Lithium Heparin), or Lavender (K EDTA).
Specimen Preparation
Allow specimen to clot completely at room temperature. Separate from cells ASAP or within 2 hours of collection. Transfer 1 mL serum or plasma to an ARUP Standard Transport Tube. (Min: 0.5 mL)
Storage/Transport Temperature
Frozen.
Unacceptable Conditions
Remarks
Stability
After separation from cells: Ambient: 24 hours; Refrigerated: 1 week; Frozen: 1 year
Reference Interval
0.54 IU/L or less | Consistent with healthy thyroid function or non-Graves thyroid or autoimmune disease. Those with healthy thyroid function typically have results less than 0.1 IU/L. |
0.55 IU/L or greater | Consistent with Graves disease (autoimmune hyperthyroidism). |
Interpretive Data
This assay specifically detects thyroid stimulating autoantibodies. For diagnostic purposes, the results obtained from this assay should be used in combination with clinical examination, patient medical history, and other findings.
Compliance Category
FDA
Note
Hotline History
N/A
CPT Codes
84445
Components
Component Test Code* | Component Chart Name | LOINC |
---|---|---|
3002288 | Thyroid Stimulating Immunoglobulin-TSI | 30567-2 |
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
- Autoimmune Thyroid Stimulator
- Thyroid Stimulating Antibody
- Thyroid-Stimulating Immunoglobulin Serum
- TSI
- TSI concentration
Thyroid Stimulating Immunoglobulin