Ordering Recommendation

Use to confirm the diagnosis of familial cerebral cavernous malformation in an individual with suggestive findings.

Mnemonic
CCM NGS
Methodology

Massively Parallel Sequencing / Genomic Microarray (Oligo-based Array)

Performed

Varies

Reported

3-6 weeks

New York DOH Approval Status
Specimens from New York clients will be sent out to a New York DOH approved laboratory, if possible.
Specimen Required
Patient Preparation
Collect

Lavender (EDTA) or Yellow (ACD Solution A or B)

Specimen Preparation

Transport 3 mL whole blood. (Min: 1.5 mL)

Storage/Transport Temperature

Refrigerated.

Unacceptable Conditions

Serum or plasma; grossly hemolyzed or frozen specimens

Remarks
Stability

Ambient: 72 hours; Refrigerated: 1 week; Frozen: Unacceptable

Reference Interval

By report

Interpretive Data

Refer to report.

Compliance Category

Laboratory Developed Test (LDT)

Note

Genes tested: CCM2, KRIT1, PDCD10

Hotline History
N/A
CPT Codes

81479

Components
Component Test Code* Component Chart Name LOINC
3002291 Cerebral Cavernous Malformation Specimen
3002292 Cerebral Cavernous Malformation Interp
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • CCM
  • familial CCL (FCCM)
Cerebral Cavernous Malformation Panel, Sequencing and Deletion/Duplication