Ordering Recommendation

Detect antibodies for P/Q type and N-type voltage-gated calcium channels. Aid in the evaluation of muscle weakness in the context neuromuscular junction disorder with or without cancer, or the diagnosis of paraneoplastic neurological syndromes.

Mnemonic
VGCC PAN
Methodology

Quantitative Radioimmunoassay

Performed

Tue

Reported

2-9 days

New York DOH Approval Status
This test is New York DOH approved.
Specimen Required
Patient Preparation
Collect

Plain Red or Serum Separator Tube (SST).

Specimen Preparation

Separate from cells ASAP or within 2 hours of collection. Transfer 1 mL to an ARUP Standard Transport Tube. (Min.: 0.2 mL)

Storage/Transport Temperature

Refrigerated.

Unacceptable Conditions

Hemolyzed or grossly lipemic specimens.

Remarks
Stability

After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 month

Reference Interval
Test Number
Components
Reference Interval
  N-Type Calcium Channel Antibody
Negative 0.0 to 69.9 pmol/L
Indeterminate 70.0 to 110.0 pmol/L
Positive 110.1 pmol/L or greater

0092628 P/Q-Type Voltage-Gated Calcium Channel (VGCC) Antibody Effective November 14, 2011
Negative 0.0 to 24.5 pmol/L
Indeterminate 24.6 to 45.6 pmol/L
Positive 45.7 pmol/L or greater

Interpretive Data



Compliance Category

Laboratory Developed Test (LDT)

Note
Hotline History
N/A
CPT Codes

83519 x2

Components
Component Test Code* Component Chart Name LOINC
0092629 P/Q-Type Calcium Channel Antibody 33980-4
3002047 N-Type Calcium Channel Antibody 33979-6
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • Lambert Eaton
  • Lambert-Eaton
  • N calcium channel
  • N VGCC Ab
  • P/Q calcium channel
  • VGCC Ab
Voltage-Gated Calcium Channel (VGCC) Antibody Panel