Ordering Recommendation

Evaluate carbohydrate malabsorption due to disaccharidase deficiency.

New York DOH Approval Status

This test is New York state approved.

Specimen Required

Patient Preparation

Biopsies of small bowel by endoscopy.

Specimen Preparation

Place two 5 mg biopsies of tissue on the wall of a small, tightly-capped plastic tube without any supporting media or an ARUP Standard Transport Tube and freeze within 2 hours of collection. (Min: 2 (two) 5 mg biopsies)

Storage/Transport Temperature

Frozen. Ship on dry ice.

Unacceptable Conditions

Specimens placed on gauze, filter paper, or any other type of support media. Tissue preserved in formalin.


Ambient: Unacceptable; Refrigerated: Unacceptable; Frozen: 6 months


Quantitative Spectrophotometry


Mon, Wed, Fri


1-6 days

Reference Interval

Component Reference Interval
Lactase Greater than or equal to 10.0 µmol/min/g protein
Maltase Greater than or equal to 100.0 µmol/min/g protein
Palatinase Greater than or equal to 9.0 µmol/min/g protein
Sucrase Greater than or equal to 25.0 µmol/min/g protein

Interpretive Data

This test was developed and its performance characteristics determined by ARUP Laboratories. It has not been cleared or approved by the US Food and Drug Administration. This test was performed in a CLIA certified laboratory and is intended for clinical purposes.

Compliance Category

Laboratory Developed Test (LDT)


Hotline History


CPT Codes



Component Test Code* Component Chart Name LOINC
2002249 Sucrase 14178-8
2002251 Lactase 1942-2
2002253 Palatinase 14168-9
2002255 Maltase 29640-0
2002487 Disaccharidase Interpretation 57779-1
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.


  • Isomaltase
  • Lactase
  • Maltase
  • Palatinase
  • Sucrase
Disaccharidase in Tissue