Assess risk for alloimmune hemolytic disease of the fetus and newborn (HDFN) or hemolytic transfusion reaction. May be ordered for parental or fetal genotyping.
Polymerase Chain Reaction/Fluorescence Monitoring
New York DOH Approval Status
Fetal genotyping: Amniotic fluid
OR Cultured amniocytes: Two T-25 flasks at 80 percent confluency.
If the client is unable to culture, order test Cytogenetics Grow and Send (ARUP test code 0040182) in addition to this test and ARUP will culture upon receipt (culturing fees will apply). If you have any questions, contact ARUP's Genetics Processing at 800-522-2787 ext. 3301.
WITH maternal cell contamination specimen (see Note): Lavender (K2EDTA), Pink (K2EDTA), or Yellow (ACD Solution A or B).
Parental genotyping: Lavender (K2EDTA), Pink (K2EDTA).
Amniotic fluid: Transport 10 mL amniotic fluid in a sterile container. (Min: 5 mL).
Cultured amniocytes: Transport two T-25 flasks at 80 percent confluency filled with culture media. Backup cultures must be retained at the client's institution until testing is complete.
Maternal cell contamination specimen: Transport 3 mL whole blood (Min: 1 mL)
Whole blood (parental genotyping): Transport 3 mL whole blood. (Min: 1 mL)
Amniotic fluid, cultured amniocytes: CRITICAL ROOM TEMPERATURE. Must be received within 48 hours of shipment due to lability of cells.
Whole blood or maternal cell contamination specimen: Refrigerated.
Plasma or serum. Specimens collected in sodium heparin tubes.
Patient History Form is available on the ARUP website or by contacting ARUP Client Services.
Fetal specimens: Ambient: 48 hours; Refrigerated: Unacceptable; Frozen: Unacceptable
Whole blood or maternal cell contamination specimen: Ambient: 72 hours; Refrigerated: 1 week; Frozen: 1 month
Refer to report
Maternal specimen is recommended for proper test interpretation if contamination of the fetal specimen from the mother is suspected. Order Maternal Cell Contamination.
|Component Test Code*||Component Chart Name||LOINC|
|3002013||KEL GENO Specimen||31208-2|
- KEL1 and KEL2 genotyping
- Kel1 heterozygosity or homozygosity assay
- Kell Antigen genotyping
- Kell/Cellano genotyping