Ordering Recommendation

May aid in the evaluation of lung inflammation or injury in various types of interstitial lung disease (ILD).

Mnemonic

SP-D

Methodology

Quantitative Enzyme-Linked Immunosorbent Assay

Performed

Tue

Reported

1-8 days

New York DOH Approval Status

This test is New York DOH approved.

Specimen Required

Patient Preparation
Collect

Plain Red.

Specimen Preparation

Allow specimen to clot completely at room temperature. Separate from cells ASAP or within 2 hours of collection. Transfer 1.5 mL serum to ARUP Standard Transport Tube. (Min: 0.5 mL)

Storage/Transport Temperature

Refrigerated.

Unacceptable Conditions

Plasma, CSF, or other body fluids. Contaminated, heat-inactivated, hemolyzed, icteric, or severely lipemic specimens.

Remarks
Stability

Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 month

Reference Interval

1-300 ng/mL

Interpretive Data

Human Surfactant Protein D (SP-D) is a non-specific indicator of lung inflammation or damage. Elevated levels are associated with various types of interstitial lung diseases (ILD).

Abnormal SP-D results should be interpreted in the appropriate clinical context. A negative result does not rule out ILD.

This test was developed and its performance characteristics determined by ARUP Laboratories. It has not been cleared or approved by the US Food and Drug Administration. This test was performed in a CLIA certified laboratory and is intended for clinical purposes.

Compliance Category

Laboratory Developed Test (LDT)

Note

Hotline History

N/A

CPT Codes

83520

Components

Component Test Code* Component Chart Name LOINC
3001970 Human Surfactant Protein D 74541-4
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.

Aliases

Human Surfactant Protein D (SP-D)