Secondary test to diagnose autoimmune disease after adrenal insufficiency confirmed.
Qualitative Enzyme-Linked Immunosorbent Assay
Serum Separator Tube (SST) or Plain Red.
Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.3 mL)
Grossly hemolyzed or lipemic specimens.
Ambient: 24 hours; Refrigerated: 1 week; Frozen: 1 month
The 21-Hydroxylase Autoantibody assay is intended for the qualitative determination of autoantibodies to steroid 21-hydroxylase in human serum.
A positive result is indicative of primary adrenal insufficiency (Addison disease). Results should be interpreted within the context of clinical symptoms, including functional adrenal testing.
Males with adrenal insufficiency and negative results for 21-hydroxylase autoantibodies should be screened for X-Linked Adrenoleukodystrophy (X-ALD) by ordering Very Long-Chain Branched Fatty Acids in Plasma (ARUP Test Code 2004250).
|Component Test Code*||Component Chart Name||LOINC|
- 21-OH Ab
- Adrenal Antibodies
- Adrenal Antibody
- Anti-Adrenal Antibody
- Hydroxylase Antibody